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Chem Impex
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Product Information

Product Name
2',3',5'-tri-O-Acetylguanosine
Brand Name
Chem Impex
Product Number
24145
CAS
6979-94-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
135465084
IUPAC Name
(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2-amino-6-oxo-1H-purin-9-yl)oxolan-2-ylmethyl acetate
InChI Key
ULXDFYDZZFYGIY-SDBHATRESA-N
SMILES
CC(=O)OCC@@H1C@H(C@H(C@@H(O1)N2C=NC3=C2N=C(NC3=O)N)OC(=O)C)OC(=O)C

Application

2',3',5'-tri-O-Acetylguanosine is widely utilized in research focused on:

Nucleic Acid Research: This compound serves as a key building block in the synthesis of modified nucleotides, which are essential for studying RNA and DNA functions and interactions.

Pharmaceutical Development: It is used in the development of antiviral drugs, particularly those targeting RNA viruses, providing a pathway for creating effective treatments.

Biotechnology: Researchers employ this compound in the production of RNA-based therapeutics, enhancing the stability and efficacy of RNA molecules in therapeutic applications.

Diagnostic Tools: It plays a role in the formulation of diagnostic assays, improving the sensitivity and specificity of tests for various diseases.

Gene Delivery Systems: This compound is incorporated into vectors for gene therapy, facilitating the safe and efficient delivery of genetic material into cells.

References Data Source From Pubchem

RNA structure promotes liquid-to-solid phase transition of short RNAs in neuronal dysfunction

Publication Name: Communications Biology
Publication Date: 2024-01-29
DOI: 10.1038/s42003-024-05828-z

Nucleobase- and DNA-Functionalized Hydrogels and Their Applications

Publication Name: Molecular Architectonics and Nanoarchitectonics
Publication Date: 2021-10-28
DOI: 10.1007/978-981-16-4189-3_14

Photochemistry of 6-amino-2-azido, 2-amino-6-azido and 2,6-diazido analogues of purine ribonucleosides in aqueous solutions

Publication Name: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Publication Date: 2014-03-01
DOI: 10.1039/c3pp50385b

Oxidative Modification of Guanine Bases Initiated by Oxyl Radicals Derived from Photolysis of Azo Compounds

Publication Name: The journal of physical chemistry. B
Publication Date: 2010-04-23
DOI: 10.1021/jp100686j

Structure and Gelation Mechanism of Tunable Guanosine-Based Supramolecular Hydrogels

Publication Name: Langmuir : the ACS journal of surfaces and colloids
Publication Date: 2010-04-12
DOI: 10.1021/la100211y