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Sku CI01346_25_G
Chem Impex
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Product Information

Product Name
Boc-L-glutamine 4-nitrophenyl ester
Brand Name
Chem Impex
Product Number
01346
CAS
15387-45-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7017891
IUPAC Name
(4-nitrophenyl) (2S)-5-amino-2-(2-methylpropan-2-yl)oxycarbonylamino-5-oxopentanoate
InChI Key
HJMMCTZLXOVMFB-LBPRGKRZSA-N
SMILES
CC(C)(C)OC(=O)NC@@H(CCC(=O)N)C(=O)OC1=CC=C(C=C1)N+(=O)O-

Application

Boc-L-glutamine 4-nitrophenyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the efficient coupling of amino acids.

Drug Development: It is employed in the development of pharmaceutical compounds, especially those targeting glutamine pathways, which are crucial in cancer metabolism and other diseases.

Bioconjugation: The ester functionality enables bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, enhancing drug delivery systems.

Analytical Chemistry: Used as a standard in chromatographic techniques, it helps in the quantification and analysis of glutamine derivatives in various samples.

Research in Neurobiology: Its role in studying neurotransmitter pathways makes it significant for research into neurological disorders, providing insights into glutamate and its analogs.

References Data Source From Pubchem

Active Esters

Publication Name: Science of Synthesis
Publication Date: 2005

The hydrolysis of primary amide groups in Asn/Gln-containing peptides

Publication Name: Russian Journal of Bioorganic Chemistry
Publication Date: 2000-06
DOI: 10.1007/bf02758662

Peptides and antitumor activity. Development and investigation of some peptides with antitumor activity

Publication Name: Acta Biologica Hungarica
Publication Date: 2000-03
DOI: 10.1007/bf03542961

Effect of obligatory replacement and conformational restriction on psychotropic activity of thyroliberin analogs

Publication Name: Russian Chemical Bulletin
Publication Date: 1998-10
DOI: 10.1007/bf02494506

A side reaction in peptide synthesis involving pyroglutamyl and glutaminyl residues

Publication Name: Peptides 1992
Publication Date: 1993
DOI: 10.1007/978-94-011-1470-7_100