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Product Information

Product Name
Boc-L-glutamine
Brand Name
Chem Impex
Product Number
00845
CAS
13726-85-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
83687
IUPAC Name
(2S)-5-amino-2-(2-methylpropan-2-yl)oxycarbonylamino-5-oxopentanoic acid
InChI Key
VVNYDCGZZSTUBC-LURJTMIESA-N
SMILES
CC(C)(C)OC(=O)NC@@H(CCC(=O)N)C(=O)O

Application

Boc-L-glutamine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protected amino acid in the synthesis of peptides, allowing for the selective incorporation of glutamine into peptide chains, which is crucial for developing therapeutic proteins.

Drug Development: It plays a significant role in the pharmaceutical industry, particularly in the design of prodrugs that enhance the solubility and bioavailability of active pharmaceutical ingredients.

Biotechnology: In biotechnological applications, Boc-L-glutamine is used in the production of recombinant proteins, helping to optimize yield and functionality in various cell systems.

Research in Metabolism: Researchers utilize this compound to study metabolic pathways involving glutamine, which is essential for understanding various diseases, including cancer and neurodegenerative disorders.

Diagnostics: It is also applied in the development of diagnostic tools that measure glutamine levels in biological samples, aiding in the early detection of metabolic disorders.

References Data Source From Pubchem

Inverse Peptide Synthesis Using Transient Protected Amino Acids

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2025
DOI: 10.1007/978-1-0716-4562-8_21

A multi-step continuous flow synthesis of pomalidomide

Publication Name: Journal of Flow Chemistry
Publication Date: 2022-04-19
DOI: 10.1007/s41981-022-00223-3

An Improved Synthesis of β-Cyano-l-Alanine Esters and Amides

Publication Name: Synlett
Publication Date: 2015-09-30
DOI: 10.1055/s-0035-1560489

Biomimetic Affinity Ligands for Immunoglobulins Based on the Multicomponent Ugi Reaction

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2012
DOI: 10.1007/978-1-61779-349-3_5

Synthesis of Thalidomide

Publication Name: Topics in Heterocyclic Chemistry
Publication Date: 2007
DOI: 10.1007/7081_2007_057