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Sku CI11962_5_G
Chem Impex
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Product Information

Product Name
Fmoc-L-glutamic acid g-methyl ester
Brand Name
Chem Impex
Product Number
11962
CAS
145038-50-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
51340556
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-methoxy-5-oxopentanoic acid
InChI Key
RULINAWEYRMHHQ-SFHVURJKSA-N
SMILES
COC(=O)CCC@@H(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Description

Fmoc-L-glutamic acid g-methyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides. Its protective Fmoc group allows for selective deprotection, facilitating the assembly of complex peptide chains.

Drug Development: In pharmaceutical research, it is used to create peptide-based drugs. Its unique structure can enhance the bioavailability and stability of therapeutic peptides.

Bioconjugation: This chemical is employed in bioconjugation processes, linking peptides to other molecules like antibodies or drugs, which is crucial for targeted therapy in cancer treatment.

Research in Neuroscience: It plays a role in studying neurotransmitter functions due to its glutamic acid component, aiding researchers in understanding synaptic transmission and neuropharmacology.

Protein Engineering: The compound is useful in modifying proteins to improve their properties, such as solubility and stability, which is essential in various biotechnological applications.

References Data Source From Pubchem

Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2020-07-01
DOI: 10.1021/acs.jmedchem.9b02119