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Sku CI03784_250_G
Chem Impex
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Product Information

Product Name
Boc-L-glutamic acid
Brand Name
Chem Impex
Product Number
03784
CAS
2419-94-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2724758
IUPAC Name
(2S)-2-(2-methylpropan-2-yl)oxycarbonylaminopentanedioic acid
InChI Key
AQTUACKQXJNHFQ-LURJTMIESA-N
SMILES
CC(C)(C)OC(=O)NC@@H(CCC(=O)O)C(=O)O

Description

Boc-L-glutamic acid is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protecting group for amino acids during peptide synthesis, allowing for the selective modification of other functional groups without interference.

Drug Development: It plays a crucial role in the design of pharmaceuticals, particularly in the development of prodrugs that enhance bioavailability and reduce side effects.

Bioconjugation: Researchers use Boc-L-glutamic acid to create bioconjugates, which are essential in targeted drug delivery systems, improving the efficacy of therapeutic agents.

Protein Engineering: It is applied in the modification of proteins to study structure-function relationships, aiding in the development of novel enzymes and therapeutic proteins.

Diagnostic Applications: The compound is also used in the synthesis of diagnostic agents, enhancing imaging techniques in medical research and clinical diagnostics.

References Data Source From Pubchem

Photobleaching-mediated charge-convertible cyclodextrin nanoparticles achieve deep tumour penetration for rectal cancer theranostics

Publication Name: Nature Nanotechnology
Publication Date: 2024-08-21
DOI: 10.1038/s41565-024-01757-4

In situ thermoresponsive supramolecular assembly for switchable circularly polarized luminescence

Publication Name: Science China Chemistry
Publication Date: 2024-05-27
DOI: 10.1007/s11426-024-2000-3

Peptidyl nitroalkene inhibitors of main protease rationalized by computational and crystallographic investigations as antivirals against SARS-CoV-2

Publication Name: Communications Chemistry
Publication Date: 2024-01-18
DOI: 10.1038/s42004-024-01104-7

Synthesis of Glycyl-(S)-5-hydroxynorvaline

Publication Name: Russian Journal of Organic Chemistry
Publication Date: 2023-11
DOI: 10.1134/s1070428023110222

Tailoring renal-clearable zwitterionic cyclodextrin for colorectal cancer-selective drug delivery

Publication Name: Nature Nanotechnology
Publication Date: 2023-04-27
DOI: 10.1038/s41565-023-01381-8