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Sku CI02414_1_G
Chem Impex
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Product Information

Product Name
Fmoc-L-glutamic acid g-tert-butyl ester a-pentafluorophenyl ester
Brand Name
Chem Impex
Product Number
02414
CAS
86061-04-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11227121
IUPAC Name
5-O-tert-butyl 1-O-(2,3,4,5,6-pentafluorophenyl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanedioate
InChI Key
AIDYQYOPUBOMTR-FQEVSTJZSA-N
SMILES
CC(C)(C)OC(=O)CCC@@H(C(=O)OC1=C(C(=C(C(=C1F)F)F)F)F)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Application

Fmoc-L-glutamic acid g-tert-butyl ester a-pentafluorophenyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions and facilitating the assembly of complex molecules in pharmaceutical research.

Drug Development: Its unique structure enhances the solubility and stability of drug candidates, making it valuable in the formulation of new therapeutic agents, particularly in oncology.

Bioconjugation: The compound is used in bioconjugation techniques to attach drugs or imaging agents to biomolecules, improving targeted delivery systems in medical applications.

Research in Neuroscience: It plays a role in studying neurotransmitter pathways by serving as a building block for compounds that mimic or interact with glutamate receptors.

Material Science: The chemical is explored in the development of advanced materials, such as polymers and coatings, due to its unique chemical properties that enhance material performance.

References Data Source From Pubchem

Picolinamidination of phosphopeptides for MALDI-TOF-TOF mass spectrometric sequencing with enhanced sensitivity

Publication Name: Journal of the American Society for Mass Spectrometry
Publication Date: 2009-09-01
DOI: 10.1016/j.jasms.2009.05.016

Role of the guanidine group in the N-terminal fragment of PTH(1–11)

Publication Name: Amino Acids
Publication Date: 2009-08-19
DOI: 10.1007/s00726-009-0337-5

Antibody Epitope Mapping Using Arrays of Synthetic Peptides

Publication Name: Antibody Engineering
Publication Date: 2003-12-05
DOI: 10.1385/1-59259-666-5:443