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Sku CI01962_5_G
Chem Impex
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Product Information

Product Name
Boc-D-glutamic acid-a-benzyl ester
Brand Name
Chem Impex
Product Number
01962
CAS
34404-30-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7010515
IUPAC Name
(4R)-4-(2-methylpropan-2-yl)oxycarbonylamino-5-oxo-5-phenylmethoxypentanoic acid
InChI Key
CVZUKWBYQQYBTF-CYBMUJFWSA-N
SMILES
CC(C)(C)OC(=O)NC@H(CCC(=O)O)C(=O)OCC1=CC=CC=C1

Application

Boc-D-glutamic acid-a-benzyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals. Its protective groups allow for selective reactions, enhancing the efficiency of peptide assembly.

Drug Development: The compound is instrumental in creating new drug candidates, especially in the field of neuropharmacology, where modifications to glutamic acid can lead to improved therapeutic profiles for neurological disorders.

Bioconjugation: It is used in bioconjugation processes to attach biomolecules to surfaces or other molecules, which is crucial in developing targeted drug delivery systems and diagnostic tools.

Research in Enzyme Inhibition: This chemical is valuable in studies aimed at understanding enzyme mechanisms, particularly those involving glutamate metabolism, which can lead to insights into metabolic disorders.

Material Science: The compound finds applications in creating polymers and materials with specific functionalities, contributing to advancements in drug delivery systems and biomaterials.

References Data Source From Pubchem

Synthesis of Novel Oxazolyl Amino Acids and Their Use in the Parallel Synthesis of Disubstituted Oxazole Libraries

Publication Name: Synthesis
Publication Date: 2018-01-19
DOI: 10.1055/s-0036-1589148

An approach to trapping .gamma.-glutamyl radical intermediates proposed for vitamin K dependent carboxylase: .alpha.,.beta.-methyleneglutamic acid

Publication Name: Journal of Medicinal Chemistry
Publication Date: 1990-02
DOI: 10.1021/jm00164a056

Synthesis of peptide analogues of prothrombin precursor sequence 5-9. Substrate specificity of vitamin K dependent carboxylase

Publication Name: Journal of Medicinal Chemistry
Publication Date: 1981-06
DOI: 10.1021/jm00138a013