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Sku CI01351_100_G
Chem Impex
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Product Information

Product Name
Boc-L-glutamic acid g-tert-butyl ester
Brand Name
Chem Impex
Product Number
01351
CAS
13726-84-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6993432
IUPAC Name
(2S)-5-(2-methylpropan-2-yl)oxy-2-(2-methylpropan-2-yl)oxycarbonylamino-5-oxopentanoic acid
InChI Key
YGSRAYJBEREVRB-VIFPVBQESA-N
SMILES
CC(C)(C)OC(=O)CCC@@H(C(=O)O)NC(=O)OC(C)(C)C

Application

Boc-L-glutamic acid g-tert-butyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups. Its stability under various conditions makes it a preferred choice for chemists.

Drug Development: In pharmaceutical research, it plays a crucial role in the design of prodrugs, which enhance the bioavailability of active pharmaceutical ingredients, improving therapeutic outcomes.

Bioconjugation: The compound is used in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in developing targeted drug delivery systems.

Research in Neuroscience: It is applied in the synthesis of neurotransmitter analogs, aiding in the study of neurological pathways and potential treatments for neurodegenerative diseases.

Material Science: The compound is also explored in creating novel polymers and materials with specific properties, contributing to advancements in fields like coatings and adhesives.

References Data Source From Pubchem

Chemoproteomic Profiling of Adenylation Domain Functions in Gramicidin S-Producing Non-ribosomal Peptide Synthetases

Publication Name: Non-Ribosomal Peptide Biosynthesis and Engineering
Publication Date: 2023
DOI: 10.1007/978-1-0716-3214-7_4

Ynamide-Mediated Synthetic Approach to Thioamide-Substituted Peptides

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2022-06-28
DOI: 10.1007/978-1-0716-2489-0_6

Diselenide–selenoester ligation for chemical protein synthesis

Publication Name: Nature Protocols
Publication Date: 2019-06-21
DOI: 10.1038/s41596-019-0180-4

Screening of efficient siRNA carriers in a library of surface-engineered dendrimers

Publication Name: Scientific Reports
Publication Date: 2016-04-28
DOI: 10.1038/srep25069

2-Diazo-1-(4-hydroxyphenyl)ethanone: a versatile photochemical and synthetic reagent

Publication Name: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Publication Date: 2014-02-01
DOI: 10.1039/c3pp50305d