5-[4-[[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]amino]quinazolin-6-yl]furan-2-carboxaldehyde|CS-0100421|231278-84-5

5-[4-[[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]amino]quinazolin-6-yl]furan-2-carboxaldehyde

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Sku TS246CS-0100421_5_G
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Product Information

Product Name
5-4-3-Chloro-4-(3-fluorobenzyl)oxyphenylaminoquinazolin-6-ylfuran-2-carboxaldehyde
Brand Name
ChemScene
Product Number
CS-0100421
CAS
231278-84-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11181296
IUPAC Name
5-4-3-chloro-4-(3-fluorophenyl)methoxyanilinoquinazolin-6-ylfuran-2-carbaldehyde
InChI Key
XQPZOUAAXRXPAM-UHFFFAOYSA-N
SMILES
C1=CC(=CC(=C1)F)COC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)C5=CC=C(O5)C=O)Cl

References Data Source From Pubchem

Direct (Hetero)arylation Reactions of (Hetero)arenes as Tools for the Step- and Atom-Economical Synthesis of Biologically Active Unnatural Compounds Including Pharmaceutical Targets
Publication Name: Synthesis
Publication Date: 2016-10-11
DOI: 10.1055/s-0036-1588303

Metabolism-Dependent Inhibition of CYP3A4 by Lapatinib: Evidence for Formation of a Metabolic Intermediate Complex with a Nitroso/Oxime Metabolite Formed via a Nitrone Intermediate
Publication Name: Drug metabolism and disposition: the biological fate of chemicals
Publication Date: 2013-05
DOI: 10.1124/dmd.113.051151

Human Metabolism of Lapatinib, a Dual Kinase Inhibitor: Implications for Hepatotoxicity
Publication Name: Drug metabolism and disposition: the biological fate of chemicals
Publication Date: 2012-01
DOI: 10.1124/dmd.111.040949

Lapatinib
Publication Name: Pharmaceutical Substances
Publication Date: 2008

Recent Advances in Pd/C-Catalyzed Coupling Reactions
Publication Name: Synthesis
Publication Date: 2006-08-15
DOI: 10.1055/s-2006-950197