(S)-(-)-5,5'-Bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole, min. 98% (S)-(-)-DM-SEGPHOS

Technical Notes:
1. Biaryl bisphos phine ligand with narrow dihedral angle. The DM-SEGPHOS ligand, as the ruthenium complex, gives superior enantios electivity and diastereoselectivity in the asymmetric hydrogenation of a-substituted-ß-ketoesters. See 15-0066. 2.Copper catalyzed enantioselective 3 + 2 cycloaddition as a route to Y amino ketones and 3-pyrrolidinones.
3.Palladium catalyzed e nantioselective addition of malonates to dihydroisoquinolines.
4.Ruthenium catalyzod enantioselective synthesis of ß amino acids by hydroge nation
5.Ruthenium catalyzed asymmetric hydrogenation of 3-quinuclidinone. See 44-0098 for Ru catalyst.
6.Diastereo- and enantioselective ruthenium- catalyzed hydrohydroxyalkylation of 2-silyl-butadienes.
References:
1.Org. Lett., 2005, 7, 1051.
2.J. Am. Chem. Soc., 2006, 128, 14010.
3.WIPO Pat. W 2005028419.
4.U.S. Pat. App. 2006047122.
5.J. Am. Chem. Soc., 2011 , 133, 1 0582.