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Sku TS246CS-7807_25_G
ChemScene
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Product Information

Product Name
Eugenol,98% (stabilized with TBC)
Brand Name
ChemScene
Product Number
CS-7807
CAS
97-53-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
3314
IUPAC Name
2-methoxy-4-prop-2-enylphenol
InChI Key
RRAFCDWBNXTKKO-UHFFFAOYSA-N
SMILES
COC1=C(C=CC(=C1)CC=C)O

Description

Product Introduction

Eugenol (CAS No. 97-53-0) is a naturally occurring phenolic aromatic compound primarily found in clove oil and other essential oils. It contains a phenolic hydroxyl group, methoxy group, and allyl side chain, giving it unique chemical reactivity and biological activity.

Due to its antioxidant, antimicrobial, anti-inflammatory, and radical-scavenging properties, Eugenol is widely used in pharmaceutical research, food science, cosmetic formulations, dental materials, organic synthesis, and biomaterials research.

In chemical research, Eugenol serves as a valuable phenolic building block for synthesizing functional molecules, polymers, and bioactive compounds. Its reactive phenolic hydroxyl group also makes it useful in polymer modification and antioxidant studies.

 

Structural Characteristics

Phenolic Hydroxyl Group (-OH)

The phenolic hydroxyl group provides:

  • Antioxidant activity
  • Hydrogen bonding capability
  • Radical scavenging ability
  • Chemical modification site

 

Methoxy Group (-OCH₃)

The methoxy group contributes:

  • Electronic effects
  • Molecular stability
  • Aromatic functionality
  • Influence on biological activity

 

Allyl Side Chain

The allyl group enables:

  • Organic modification reactions
  • Polymerization studies
  • Functional molecule synthesis
  • Chemical derivatization

 

Key Research Applications

1. Antioxidant Research

Eugenol is widely studied as a natural antioxidant compound.

Applications include:

  • Free radical scavenging studies
  • Oxidative stress research
  • Antioxidant mechanism studies
  • Food antioxidant development
  • Functional material stabilization

The phenolic structure enables electron donation and radical neutralization.

 

2. Pharmaceutical and Biomedical Research

Eugenol is investigated for various biological activities.

Applications include:

  • Antimicrobial studies
  • Anti-inflammatory research
  • Bioactive compound development
  • Drug delivery research
  • Biomaterial modification

 

3. Dental Materials and Oral Care Research

Eugenol is an important component in dental applications.

Applications include:

  • Zinc oxide–eugenol dental cement research
  • Dental restorative materials
  • Root canal materials
  • Antimicrobial dental formulations

Its interaction with zinc oxide forms materials with useful mechanical and biological properties.

 

4. Food and Flavor Research

Eugenol is widely used in food-related research.

Applications include:

  • Natural flavor studies
  • Food preservation research
  • Antioxidant additives
  • Food packaging materials

Its aromatic properties and biological activity make it valuable in food science.

 

5. Polymer and Material Chemistry

Eugenol serves as a renewable aromatic building block.

Applications include:

  • Bio-based polymer synthesis
  • Functional polymer modification
  • Resin development
  • Coating materials
  • Sustainable materials research

 

6. Organic Synthesis

Eugenol is used as a starting material for chemical synthesis.

Applications include:

  • Phenolic derivative synthesis
  • Pharmaceutical intermediates
  • Functional organic molecules
  • Chemical modification studies

 

Advantages

  • Naturally derived aromatic compound
  • Strong antioxidant capability
  • Multifunctional chemical structure
  • Renewable bio-based building block
  • Suitable for pharmaceutical and material research
  • Broad compatibility with organic synthesis

 

Storage & Handling

  • Store in a cool, dry place.
  • Protect from light and air exposure.
  • Keep container tightly sealed.
  • Avoid prolonged heating.

Eugenol may oxidize during long-term exposure to air and light.

 

Research Areas

  • Natural product chemistry
  • Pharmaceutical research
  • Food science
  • Dental materials
  • Polymer chemistry
  • Antioxidant research
  • Biomaterials

FAQ

Q1: What is Eugenol?

A: Eugenol (CAS No. 97-53-0) is a phenolic natural compound mainly obtained from clove oil and widely used in pharmaceutical, food, dental, and chemical research.

 

Q2: What is Eugenol used for?

A: Eugenol is mainly used in:

  • Antioxidant research
  • Dental material studies
  • Food preservation research
  • Pharmaceutical development
  • Polymer synthesis

 

Q3: Is Eugenol a natural compound?

A: Yes. Eugenol is a naturally occurring phenolic compound found mainly in clove oil and several aromatic plants.

 

Q4: Why does Eugenol have antioxidant activity?

A: The phenolic hydroxyl group can donate hydrogen atoms to neutralize free radicals, contributing to antioxidant properties.

 

Q5: Is Eugenol used in dental materials?

A: Yes. Eugenol is widely studied with zinc oxide systems for dental cement and restorative material applications.

 

Q6: Can Eugenol be used in polymer synthesis?

A: Yes. The allyl group and phenolic structure make Eugenol a useful renewable building block for functional polymers and resins.

 

Q7: What is the difference between Eugenol and Isoeugenol?

Property Eugenol Isoeugenol
CAS No. 97-53-0 97-54-1
Double Bond Position Allyl group Propenyl group
Main Use Dental, antioxidant, synthesis Flavor, fragrance, synthesis

 

Q8: How should Eugenol be stored?

A: Eugenol should be stored in a sealed container away from light, heat, and oxygen to maintain stability.

References Data Source From Pubchem

Development of bilayer film of Persian acorn starch and zein electrospun nanofibers loaded with cinnamon essential oil for shelf-life extension of rainbow trout fillet

Publication Name: Food Production, Processing and Nutrition
Publication Date: 2026-03-04
DOI: 10.1186/s43014-025-00361-w

Development and optimization of bioactive edible films from acetylated corn starch, glycerol, and citronella essential oil: mechanical, barrier, and antifungal characterization

Publication Name: Journal of Food Measurement and Characterization
Publication Date: 2026-03-04
DOI: 10.1007/s11694-026-04119-x

Essential oils as biopesticides: contact toxicity, volatile profiling, and molecular target interaction in Caryedon serratus

Publication Name: International Journal of Tropical Insect Science
Publication Date: 2026-03-03
DOI: 10.1007/s42690-026-01789-4

Correction: The emerging pathogen Candida auris: host interactions and disease drivers

Publication Name: Journal of Biomedical Science
Publication Date: 2026-02-21
DOI: 10.1186/s12929-026-01230-5|10.1186/s12929-026-01234-1