2’-Deoxy-2’-fluoro-b-D-arabinocytidine|CS-0186931|56632-83-8

2’-Deoxy-2’-fluoro-b-D-arabinocytidine

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Sku TS246CS-0186931_100_MG
ChemScene
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Product Information

Product Name
2’-Deoxy-2’-fluoro-b-D-arabinocytidine
Brand Name
ChemScene
Product Number
CS-0186931
CAS
56632-83-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
151382
IUPAC Name
4-amino-1-(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-ylpyrimidin-2-one
InChI Key
NVZFZMCNALTPBY-PXBUCIJWSA-N
SMILES
C1=CN(C(=O)N=C1N)C@H2C@H(C@@H(C@H(O2)CO)O)F

References

Synthesis and anti-HCV activity of 3′,4′-oxetane nucleosides
Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2010-08-01
DOI: 10.1016/j.bmcl.2010.06.025

The Design, Synthesis, and Antiviral Activity of Monofluoro and Difluoro Analogues of 4′-Azidocytidine against Hepatitis C Virus Replication: The Discovery of 4′-Azido-2′-deoxy-2′-fluorocytidine and 4′-Azido-2′-dideoxy-2′,2′-difluorocytidine
Publication Name: Journal of Medicinal Chemistry
Publication Date: 2009-04-02
DOI: 10.1021/jm801595c

2'-deoxy-4'-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2'-alpha-hydroxyl groups
Publication Name: The Journal of biological chemistry
Publication Date: 2008-01-25
DOI: 10.1074/jbc.m708929200

Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication
Publication Name: Journal of Medicinal Chemistry
Publication Date: 2005-07-26
DOI: 10.1021/jm0502788

Structure−Activity Relationships of 1-(2-Deoxy-2-fluoro-β-l-arabino- furanosyl)pyrimidine Nucleosides as Anti-Hepatitis B Virus Agents
Publication Name: Journal of Medicinal Chemistry
Publication Date: 1996-01-01
DOI: 10.1021/jm960098l