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Sku CI14009_25_G
Chem Impex
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Product Information

Product Name
Fmoc-L-cysteine hydrate
Brand Name
Chem Impex
Product Number
14009
CAS
135248-89-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11024349
IUPAC Name
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-sulfanylpropanoic acid
InChI Key
RMTDKXQYAKLQKF-INIZCTEOSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@@H(CS)C(=O)O

Description

Fmoc-L-cysteine hydrate is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.

Drug Development: Its role in modifying drug candidates enhances their stability and bioavailability, making it valuable in pharmaceutical research for developing new therapeutics.

Bioconjugation: Fmoc-L-cysteine hydrate is used to attach biomolecules to surfaces or other compounds, facilitating the creation of targeted drug delivery systems and diagnostics.

Protein Engineering: Researchers employ this compound to introduce thiol groups into proteins, which can be crucial for studying protein interactions and functions.

Antioxidant Research: Its properties make it a subject of study in exploring antioxidant mechanisms, contributing to the understanding of cellular protection against oxidative stress.

References Data Source From Pubchem

Designing supramolecular catalytic systems for mammalian synthetic metabolism

Publication Name: Nature Reviews Materials
Publication Date: 2025-04-29
DOI: 10.1038/s41578-025-00801-6

Upstream Proteolysis by Ste24 does not Require a C-Terminal Methyl Ester as Revealed Using 33-Residue a-Factor Precursor Peptide Substrates Synthesized via Epimerization-Free Methods

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2025-01-06
DOI: 10.1007/s10989-024-10677-9

Double Conjugation Using Mercapto-Acryloyl and Alkyne-Azide Reactions for the Synthesis of Branched Multiantigenic Vaccine Candidates

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2021
DOI: 10.1007/978-1-0716-1617-8_13

Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2020-07-01
DOI: 10.1021/acs.jmedchem.9b02119

Chemical proteomics reveals new targets of cysteine sulfinic acid reductase

Publication Name: Nature Chemical Biology
Publication Date: 2018-09-03
DOI: 10.1038/s41589-018-0116-2