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Chem Impex
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Product Information

Product Name
Fmoc-S-acetamidomethyl-L-cysteine
Brand Name
Chem Impex
Product Number
02396
CAS
86060-81-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
128799
IUPAC Name
(2R)-3-(acetamidomethylsulfanyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
InChI Key
CSMYOORPUGPKAP-IBGZPJMESA-N
SMILES
CC(=O)NCSCC@@H(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Application

Fmoc-S-acetamidomethyl-L-cysteine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), enabling researchers to create complex peptide structures efficiently.

Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, especially those targeting specific proteins or enzymes.

Bioconjugation: The compound is used in bioconjugation processes, allowing for the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted therapies and diagnostics.

Research in Protein Engineering: It plays a significant role in protein engineering, where modifications can enhance protein stability and activity, leading to better therapeutic outcomes.

Analytical Chemistry: Fmoc-S-acetamidomethyl-L-cysteine is employed in analytical techniques to study protein interactions and modifications, providing insights into biological processes.

References Data Source From Pubchem

Total Chemical Synthesis and Evaluation of the Antimicrobial Properties of Porcine β-Defensin 5 Against Gram-Positive and Gram-Negative Bacteria

Publication Name: Probiotics and Antimicrobial Proteins
Publication Date: 2026-03-04
DOI: 10.1007/s12602-025-10870-2

Water-based coupling of amino acids for sustainable solid-phase peptide synthesis

Publication Name: Nature Sustainability
Publication Date: 2026-02-03
DOI: 10.1038/s41893-025-01761-z

A deep learning framework (CreoPep) for target-specific design and optimization of conotoxin peptides

Publication Name: Communications Chemistry
Publication Date: 2026-01-09
DOI: 10.1038/s42004-025-01885-5

Mirror-Image Human Serum Albumin Domain III as a Tool for Analyzing Site II-Dependent Molecular Recognition

Publication Name: Synthesis of Functional Characterization of Protein Domains for the Development of Mirror-Image Therapeutics
Publication Date: 2026
DOI: 10.1007/978-981-95-5366-2_3

Ruthenium-Catalyzed One-pot Peptide Ligation

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2025
DOI: 10.1007/978-1-0716-4486-7_2