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Chem Impex
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Product Information

Product Name
Fmoc-S-trityl-L-cysteine
Brand Name
Chem Impex
Product Number
00177
CAS
103213-32-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
128239
IUPAC Name
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-tritylsulfanylpropanoic acid
InChI Key
KLBPUVPNPAJWHZ-UMSFTDKQSA-N
SMILES
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)SCC@@H(C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46

Application

Fmoc-S-trityl-L-cysteine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protecting group for cysteine residues in peptide synthesis, allowing for the selective modification of peptides without affecting other functional groups.

Drug Development: It plays a crucial role in the development of peptide-based drugs, particularly those targeting specific receptors or enzymes, enhancing their efficacy and stability.

Bioconjugation: Researchers use it in bioconjugation strategies, linking peptides to various biomolecules, which is essential in creating targeted therapies and diagnostics.

Protein Engineering: The compound aids in the design of novel proteins with enhanced properties, such as increased stability or improved binding affinity, which is vital in biotechnology applications.

Research in Cancer Therapeutics: Its application in synthesizing peptides that can inhibit cancer cell growth is a promising area, providing potential pathways for new treatments.

References Data Source From Pubchem

Identification of an αvβ3-targeting bicyclic peptide with atypical norArg-Gly-Asp sequence

Publication Name: Communications Chemistry
Publication Date: 2026-01-12
DOI: 10.1038/s42004-026-01886-y

A deep learning framework (CreoPep) for target-specific design and optimization of conotoxin peptides

Publication Name: Communications Chemistry
Publication Date: 2026-01-09
DOI: 10.1038/s42004-025-01885-5

A novel peptide-compound conjugate alleviates endotoxin-induced inflammation via NF-κB/MAPK modulation

Publication Name: Journal of molecular medicine (Berlin, Germany)
Publication Date: 2025-12-23
DOI: 10.1007/s00109-025-02608-y

Novel cyclic heptapeptides as potential therapeutics against methicillin-resistant Staphylococcus aureus infections

Publication Name: Naunyn-Schmiedeberg's Archives of Pharmacology
Publication Date: 2025-12-08
DOI: 10.1007/s00210-025-04863-9

Genetic variance in the murine defensin locus modulates glucose homeostasis

Publication Name: The EMBO Journal
Publication Date: 2025-09-09
DOI: 10.1038/s44318-025-00555-5