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Sku CI17244_1_G
Chem Impex
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Product Information

Product Name
2-Amino-4-hydroxybenzothiazole
Brand Name
Chem Impex
Product Number
17244
CAS
7471-03-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
24057
IUPAC Name
2-amino-1,3-benzothiazol-4-ol
InChI Key
PFQJPSASUCHKRO-UHFFFAOYSA-N
SMILES
C1=CC(=C2C(=C1)SC(=N2)N)O

Application

2-Amino-4-hydroxybenzothiazole is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-cancer agents and antimicrobial drugs, enhancing therapeutic efficacy.

Dyes and Pigments: It is used in the production of dyes, particularly in textile and paper industries, providing vibrant colors and improved colorfastness compared to traditional dyes.

Analytical Chemistry: The compound acts as a reagent in analytical methods, including spectrophotometry, allowing for the detection and quantification of metal ions in environmental samples.

Biological Research: It is employed in studies investigating enzyme inhibition and protein interactions, offering insights into biochemical pathways and potential drug targets.

Material Science: This chemical is utilized in the formulation of rubber and plastics, enhancing thermal stability and mechanical properties, which is crucial for manufacturing durable products.

References Data Source From Pubchem

Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel

Publication Name: iScience
Publication Date: 2024-02-16
DOI: 10.1016/j.isci.2024.108907

Covalent inhibition of NSD1 histone methyltransferase

Publication Name: Nature Chemical Biology
Publication Date: 2020-08-31
DOI: 10.1038/s41589-020-0626-6

A Novel System for the Synthesis of 2-Aminobenzthiazoles using Sodium Dichloroiodate

Publication Name: Synlett
Publication Date: 2012-08-17
DOI: 10.1055/s-0032-1317080

Design, synthesis and activity of benzothiazole-based inhibitors of NO production in LPS-activated macrophages

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2010-11-01
DOI: 10.1016/j.bmcl.2010.08.112

Aminoindazole PDK1 Inhibitors: A Case Study in Fragment-Based Drug Discovery

Publication Name: ACS Medicinal Chemistry Letters
Publication Date: 2010-07-22
DOI: 10.1021/ml100136n