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Sku CI07339_1_G
Chem Impex
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Product Information

Product Name
Fmoc-4-hydrazinobenzoic acid
Brand Name
Chem Impex
Product Number
07339
CAS
214475-53-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2756155
IUPAC Name
4-2-(9H-fluoren-9-ylmethoxycarbonyl)hydrazinylbenzoic acid
InChI Key
MLVJMSRGLQCZDE-UHFFFAOYSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NNC4=CC=C(C=C4)C(=O)O

Application

Fmoc-4-hydrazinobenzoic acid is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the introduction of hydrazine functionalities.

Drug Development: It is used in the design of novel pharmaceutical compounds, especially those targeting specific biological pathways, due to its ability to form stable conjugates with various biomolecules.

Bioconjugation: The chemical is effective in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is crucial in the development of targeted drug delivery systems.

Diagnostic Applications: It finds applications in the creation of diagnostic agents, particularly in imaging techniques where specific targeting of cells or tissues is required.

Research in Cancer Therapeutics: The compound is being explored for its potential in cancer research, particularly in the development of hydrazine-based prodrugs that can selectively target cancer cells.

References Data Source From Pubchem

SPOT Synthesis as a Tool to Study Protein–Protein Interactions

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2011
DOI: 10.1007/978-1-61779-043-0_8