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Chem Impex
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Product Information

Product Name
3-N-Maleimidobenzoic acid
Brand Name
Chem Impex
Product Number
06287
CAS
17057-07-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
86926
IUPAC Name
3-(2,5-dioxopyrrol-1-yl)benzoic acid
InChI Key
ZJGBFJBMTKEFNQ-UHFFFAOYSA-N
SMILES
C1=CC(=CC(=C1)N2C(=O)C=CC2=O)C(=O)O

Application

3-N-Maleimidobenzoic acid is widely utilized in research focused on

Bioconjugation: This compound is commonly used to create stable linkages between biomolecules, such as proteins and antibodies, enhancing their functionality in drug delivery systems.

Diagnostics: It plays a crucial role in the development of diagnostic tools, particularly in the labeling of biomolecules for imaging techniques, improving the sensitivity and specificity of assays.

Material Science: In polymer chemistry, it is employed to modify surfaces and improve adhesion properties, which is beneficial in creating advanced materials with tailored characteristics.

Drug Development: The compound is significant in the synthesis of new pharmaceuticals, particularly in the design of targeted therapies that require precise molecular interactions.

Research Applications: It is frequently used in academic and industrial research settings to study protein interactions and dynamics, providing insights that can lead to innovative solutions in biotechnology.

References Data Source From Pubchem

Synthesis, Biological Screening, and Molecular Dockingof Drug Carrier Maleimide Derivatives

Publication Name: Russian Journal of Bioorganic Chemistry
Publication Date: 2024-06
DOI: 10.1134/s1068162024030245

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells

Publication Name: Biochemical and Biophysical Research Communications
Publication Date: 2023-10-30
DOI: 10.1016/j.bbrc.2023.08.050

A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2

Publication Name: The Journal of biological chemistry
Publication Date: 2022-08
DOI: 10.1016/j.jbc.2022.102228

Synthetic and biological studies on some new camphor thiazolidinones

Publication Name: Journal of the Iranian Chemical Society
Publication Date: 2021-03-15
DOI: 10.1007/s13738-021-02228-6

Synthesis of Functionalized Poly(N-(3-carboxyphenyl)maleimide-alt-styrene) and Its Heat-Resistance Mechanism

Publication Name: Polymer Science, Series B
Publication Date: 2020-07
DOI: 10.1134/s1560090420040119