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Chem Impex
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Product Information

Product Name
3-Maleimidobenzoic acid N-hydroxysuccinimide ester
Brand Name
Chem Impex
Product Number
01736
CAS
58626-38-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
93861
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)benzoate
InChI Key
LLXVXPPXELIDGQ-UHFFFAOYSA-N
SMILES
C1CC(=O)N(C1=O)OC(=O)C2=CC(=CC=C2)N3C(=O)C=CC3=O

Application

3-Maleimidobenzoic acid N-hydroxysuccinimide ester is widely utilized in research focused on:

Bioconjugation: This compound is commonly used to link biomolecules, such as proteins and antibodies, to other molecules, enhancing their functionality in drug delivery systems.

Diagnostics: It plays a crucial role in the development of diagnostic assays, allowing for the precise labeling of biomolecules, which improves the sensitivity and specificity of tests.

Protein Engineering: Researchers leverage this compound to modify proteins for various applications, including the creation of novel therapeutics that can better target diseases.

Vaccine Development: Its ability to facilitate the conjugation of antigens to carriers makes it valuable in designing more effective vaccines that elicit stronger immune responses.

Research in Cancer Therapy: The compound is utilized in the development of targeted cancer therapies, where it helps to attach cytotoxic agents to cancer-targeting antibodies, improving treatment efficacy.

References

Aptamer–Field-Effect Transistors for Small-Molecule Sensing in Complex Environments

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2023
DOI: 10.1007/978-1-0716-2695-5_14

Development of ELISA and chemiluminescence enzyme immunoassay for quantification of histamine in drug products and food samples

Publication Name: Analytical and Bioanalytical Chemistry
Publication Date: 2020-06-01
DOI: 10.1007/s00216-020-02730-5

Preparation and Detection of Glycan-Binding Activity of Influenza Virus

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2020
DOI: 10.1007/978-1-0716-0430-4_49

Receptor-Binding Assays of Enterovirus D68

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2020
DOI: 10.1007/978-1-0716-0430-4_54

Generating the Blood Exposome Database Using a Comprehensive Text Mining and Database Fusion Approach

Publication Name: Environmental Health Perspectives
Publication Date: 2019-09
DOI: 10.1289/ehp4713