Cat. No JK281281_25_G
J&K Chemical

Product Information

Product Name
5,5'-Dithiobis(2-nitrobenzoic acid), 99%
Brand Name
J&K
Product Number
281281
CAS
69-78-3
Molecular Formula
C14H8N2O8S2
Molecular Weight
396.36
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6254
IUPAC Name
5-(3-carboxy-4-nitrophenyl)disulfanyl-2-nitrobenzoic acid
InChI Key
KIUMMUBSPKGMOY-UHFFFAOYSA-N
SMILES
C1=CC(=C(C=C1SSC2=CC(=C(C=C2)N+(=O)O-)C(=O)O)C(=O)O)N+(=O)O-

Properties

Melting Point
240-245

Safety Information

Signal Word
Warning
Hazard Statement
H315
H319
H335
Precautionary Statement
P280
P321
P261
P271
P319
P405
P501
P302+P352
P332+P317
P362+P364
P264+P265
P305+P351+P338
P337+P317
P304+P340
P403+P233

Application

5,5'-Dithiobis(2-nitrobenzoic acid) is widely utilized in research focused on:

Biochemical Assays: This compound is commonly used as a reagent in biochemical assays to measure thiol concentrations, helping researchers understand cellular redox states.

Protein Labeling: It serves as a labeling agent for proteins, allowing scientists to track and study protein interactions and functions in various biological systems.

Drug Development: In pharmaceutical research, it aids in the development of drugs targeting oxidative stress-related diseases by providing insights into thiol-disulfide exchange reactions.

Environmental Monitoring: The compound is utilized in environmental chemistry to detect and quantify thiol compounds in samples, which is crucial for assessing pollution levels.

Analytical Chemistry: It plays a role in analytical methods for the detection of heavy metals, enhancing the sensitivity and specificity of tests in various industrial applications.

References Data Source From Pubchem

Egg white rice-shaped analogue enhances satiety hormones and glycemic control in healthy men: a randomized unblinded crossover trial

Publication Name: Food Production, Processing and Nutrition
Publication Date: 2026-02-28
DOI: 10.1186/s43014-025-00360-x

Quercetin mitigates size-dependent oxidative and metabolic toxicity of citrate-coated silver nanoparticles in human erythrocytes

Publication Name: Archives of Toxicology
Publication Date: 2026-02-17
DOI: 10.1007/s00204-026-04308-z

Modeling and optimization of pea protein hydrolysis: linking process parameters to technological functionality

Publication Name: European Food Research and Technology
Publication Date: 2026-02-09
DOI: 10.1007/s00217-026-05037-4

Gastroprotective effect of Kahweol against ethanol-induced gastric ulcer by employing in silico, in vitro and in vivo approaches

Publication Name: Naunyn-Schmiedeberg's Archives of Pharmacology
Publication Date: 2026-02-04
DOI: 10.1007/s00210-026-05011-7

The single and combined effects of deltamethrin and polyethylene microplastics on the development and biochemical responses of Xenopus laevis in early life stages

Publication Name: Ecotoxicology (London, England)
Publication Date: 2026-01-23
DOI: 10.1007/s10646-026-03028-5

5,5'-Dithiobis(2-nitrobenzoic acid), 99%

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