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Chem Impex
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Product Information

Product Name
2-Chlorobenzimidazole
Brand Name
Chem Impex
Product Number
31112
CAS
4857-06-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
78572
IUPAC Name
2-chloro-1H-benzimidazole
InChI Key
AYPSHJCKSDNETA-UHFFFAOYSA-N
SMILES
C1=CC=C2C(=C1)NC(=N2)Cl

Application

2-Chlorobenzimidazole is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-cancer and anti-inflammatory agents.

Agricultural Chemicals: It is used in the formulation of fungicides and herbicides, helping to protect crops from disease and enhance agricultural productivity.

Material Science: The compound is incorporated into polymers and coatings, providing enhanced chemical resistance and durability, which is beneficial in various industrial applications.

Research Reagents: As a versatile reagent, it is employed in laboratory settings for the synthesis of other chemical compounds, aiding researchers in developing new materials and drugs.

Biochemical Studies: 2-Chlorobenzimidazole is used in studies related to enzyme inhibition and receptor binding, contributing to our understanding of biological processes and disease mechanisms.

References Data Source From Pubchem

Study on the metal interface adsorption behavior of nitrogen heterocyclic corrosion inhibitors

Publication Name: Applied Physics A
Publication Date: 2025-10-31
DOI: 10.1007/s00339-025-09043-3

A scaffold repositioning approach: dihydroBenzoImidazoTriazineDione (BITD) derivatives as selective ALDH1A1 inhibitors

Publication Name: Molecular Diversity
Publication Date: 2025-04-04
DOI: 10.1007/s11030-025-11179-6

Design, synthesis, and evaluation of anxiolytic activity of 2-(4-phenylpiperazin-1-yl)-1H-benz[d][d]imidazole derivatives

Publication Name: Future Journal of Pharmaceutical Sciences
Publication Date: 2024-03-29
DOI: 10.1186/s43094-024-00626-0

Durchflusschemie als Werkzeug zur Arzneimittelforschung: eine medizinchemische Perspektive

Publication Name: Flow-Chemie für die Synthese von Heterocyclen
Publication Date: 2024
DOI: 10.1007/978-3-031-51912-3_7

Investigation of the solvent effect, regioselectivity, and the mechanism of the cycloaddition reaction between 2-chlorobenzimidazole and benzonitrile oxide

Publication Name: Chemistry of Heterocyclic Compounds
Publication Date: 2023-03
DOI: 10.1007/s10593-023-03177-z