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Chem Impex
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Product Information

Product Name
5-Amino-2-(trifluoromethyl)benzimidazole dihydrochloride
Brand Name
Chem Impex
Product Number
28517
CAS
3671-66-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
19345
IUPAC Name
2-(trifluoromethyl)-3H-benzimidazol-5-amine
InChI Key
CKEKFQLHCAZGSP-UHFFFAOYSA-N
SMILES
C1=CC2=C(C=C1N)NC(=N2)C(F)(F)F

Application

5-Amino-2-(trifluoromethyl)benzimidazole dihydrochloride is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-cancer and anti-inflammatory drugs.

Agricultural Chemistry: It is used in the formulation of agrochemicals, enhancing the effectiveness of pesticides and herbicides, which helps in improving crop yields.

Material Science: The compound is explored for its potential in creating advanced materials, such as polymers with enhanced thermal and chemical resistance.

Biochemical Research: It acts as a research tool in studying enzyme inhibition and receptor interactions, providing insights into biological pathways and disease mechanisms.

Fluorinated Compound Research: Due to its trifluoromethyl group, it is valuable in the study of fluorinated compounds, which are known for their unique properties and applications in various fields.

References Data Source From Pubchem

A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density

Publication Name: Nature Communications
Publication Date: 2017-04-24
DOI: 10.1038/ncomms15123

Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design

Publication Name: Bioorganic & Medicinal Chemistry
Publication Date: 2017-02-15
DOI: 10.1016/j.bmc.2017.01.012

High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors

Publication Name: Antiviral Research
Publication Date: 2011-09
DOI: 10.1016/j.antiviral.2011.06.006

Pesticide Science., 15(31), 1984