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Product Information

Product Name
Na-Fmoc-L-arginine
Brand Name
Chem Impex
Product Number
01640
CAS
91000-69-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2724631
IUPAC Name
(2S)-5-(diaminomethylideneamino)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid
InChI Key
DVBUCBXGDWWXNY-SFHVURJKSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@@H(CCCN=C(N)N)C(=O)O

Application

Na-Fmoc-L-arginine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups. This is crucial in the development of complex peptides for pharmaceuticals.

Drug Development: Its application in drug design helps in creating more effective therapeutic agents by enhancing the stability and bioavailability of peptide-based drugs, which is vital in treating various diseases.

Bioconjugation: Na-Fmoc-L-arginine is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, improving the delivery and efficacy of drugs in targeted therapies.

Research in Cancer Therapeutics: This compound is instrumental in developing cancer treatments, as it can be incorporated into peptide sequences that target cancer cells specifically, minimizing side effects compared to traditional therapies.

Protein Engineering: It is also applied in the field of protein engineering, where it aids in the design of proteins with enhanced properties, such as increased stability or altered activity, which can lead to advancements in biotechnology and medicine.

References Data Source From Pubchem

Synthetic Peptide-Based Thrombin Inhibitors: a Potential Anticoagulant Approach

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2025-04-07
DOI: 10.1007/s10989-025-10715-0

Rapid discovery of cyclic peptide protein aggregation inhibitors by continuous selection

Publication Name: Nature Chemical Biology
Publication Date: 2025-01-13
DOI: 10.1038/s41589-024-01823-x

Multiple reaction monitoring assays for large-scale quantitation of proteins from 20 mouse organs and tissues

Publication Name: Communications Biology
Publication Date: 2024-01-02
DOI: 10.1038/s42003-023-05687-0

Proteomic Approach to Investigating Expression, Localization, and Functions of the SOWAHD Gene Protein Product during Granulocytic Differentiation

Publication Name: Biochemistry. Biokhimiia
Publication Date: 2023-10
DOI: 10.1134/s000629792310019x

Absolute Quantitative Targeted Proteomics Assays for Plasma Proteins

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2023
DOI: 10.1007/978-1-0716-2978-9_27