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Product Information

Product Name
Tianeptine sodium salt hydrate
Brand Name
Chem Impex
Product Number
38318
CAS
30123-17-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
23663953
IUPAC Name
sodium 7-(3-chloro-6-methyl-5,5-dioxo-11H-benzoc2,1benzothiazepin-11-yl)aminoheptanoate
InChI Key
ZLBSUOGMZDXYKE-UHFFFAOYSA-M
SMILES
CN1C2=CC=CC=C2C(C3=C(S1(=O)=O)C=C(C=C3)Cl)NCCCCCCC(=O)O-.Na+

Application

Product Introduction

Tianeptine Sodium Salt (CAS No. 30123-17-2) is a pharmaceutical research compound widely used in neuroscience, pharmacology, analytical chemistry, and drug development. As the sodium salt form of tianeptine, it offers improved aqueous solubility, making it suitable for laboratory studies involving formulation development, analytical method validation, and preclinical research.

This compound is commonly employed as a reference material in pharmaceutical analysis and as a research tool for investigating biochemical and pharmacological mechanisms. It is intended for research use only (RUO) and is not intended for human or veterinary use.

Chemical Properties

  • Chemical Name: Tianeptine Sodium Salt
  • CAS Number: 30123-17-2
  • Molecular Formula: C₂₁H₂₄ClN₂NaO₄S
  • Molecular Weight: 458.93
  • Appearance: White to off-white crystalline powder
  • Solubility: Soluble in water and polar solvents

Chemical Characteristics

  • Sodium salt form with enhanced water solubility
  • Suitable for analytical and formulation studies
  • Stable under recommended storage conditions
  • Appropriate for pharmaceutical research applications

Tianeptine sodium salt hydrate is widely utilized in research focused on:

Antidepressant Research: This compound is primarily studied for its unique antidepressant properties, offering potential alternatives to traditional SSRIs. Researchers explore its mechanisms to provide insights into mood regulation.

Neuroprotection: It has shown promise in protecting neurons from damage, making it a candidate for studies in neurodegenerative diseases like Alzheimer's and Parkinson's, where preserving brain health is crucial.

Stress and Anxiety Management: Tianeptine sodium salt hydrate is investigated for its effects on stress and anxiety, providing a basis for developing therapies that could improve mental health outcomes without the side effects commonly associated with other medications.

Chronic Pain Treatment: Its potential analgesic properties are being explored, particularly in conditions where traditional pain management strategies are ineffective, offering hope for patients with chronic pain syndromes.

Behavioral Studies: The compound is used in behavioral research to understand its impact on cognitive functions and emotional responses, aiding in the development of new psychological therapies.

Recommended Experimental Conditions

Parameter Recommended Conditions
Analytical Method HPLC, UPLC, LC-MS/MS
Solvent Water, methanol, or appropriate analytical solvents
Storage Temperature 2–8°C or according to laboratory protocol
Light Protection Recommended
Sample Preparation Prepare fresh analytical solutions when possible

Experimental conditions should be optimized according to the analytical method and research protocol.

FAQ

Frequently Asked Questions (FAQ)

What is Tianeptine Sodium Salt used for?
It is primarily used for pharmaceutical research, analytical method development, quality control, and laboratory investigations.

 

Is this product intended for therapeutic or clinical use?
No. This product is supplied for research use only (RUO) and is not intended for human or veterinary use.

 

Which analytical techniques are commonly used with Tianeptine Sodium Salt?
It is commonly analyzed using HPLC, UPLC, LC-MS/MS, and other chromatographic techniques.

 

Why is the sodium salt form commonly used in research?
The sodium salt generally provides improved aqueous solubility, making it more suitable for laboratory preparation and analytical applications.

 

Can this compound be used as a reference standard?
Yes. It is frequently used as a reference material for analytical method development, quality control, and pharmaceutical research.

 

What research fields commonly use this compound?
It is widely used in pharmaceutical sciences, analytical chemistry, pharmacokinetics, and drug metabolism research.

 

How should Tianeptine Sodium Salt be stored?
Store it in a cool, dry, and light-protected environment with the container tightly sealed to maintain product stability.

 

Can this compound be used for stability studies?
Yes. It is suitable for stability testing, impurity profiling, and analytical method validation in laboratory settings.

References

Systematic Review of Clinical Case Reports Involving Tianeptine Products: “Gas Station Heroin” Hype or Fact?

Publication Name: Current Addiction Reports
Publication Date: 2025-03-22
DOI: 10.1007/s40429-025-00640-z

Opioid-like adverse effects of tianeptine in male rats and mice

Publication Name: Psychopharmacology
Publication Date: 2022-02-24
DOI: 10.1007/s00213-022-06093-w

Mu opioid receptors on hippocampal GABAergic interneurons are critical for the antidepressant effects of tianeptine

Publication Name: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Publication Date: 2021-09-30
DOI: 10.1038/s41386-021-01192-2

A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome

Publication Name: Cell Reports
Publication Date: 2021-04-27
DOI: 10.1016/j.celrep.2021.109040

Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors

Publication Name: Proceedings of the National Academy of Sciences of the United States of America
Publication Date: 2020-11-23
DOI: 10.1073/pnas.2005463117