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Sku CI07380_25_G
Chem Impex
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Product Information

Product Name
Fmoc-3-(4-thiazolyl)-L-alanine
Brand Name
Chem Impex
Product Number
07380
CAS
205528-32-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7020858
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1,3-thiazol-4-yl)propanoic acid
InChI Key
LSBAZFASKHLHKB-IBGZPJMESA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@@H(CC4=CSC=N4)C(=O)O

Application

Fmoc-3-(4-thiazolyl)-L-alanine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.

Drug Development: Its unique thiazole moiety enhances the biological activity of peptides, making it valuable in the pharmaceutical industry for developing new drugs targeting specific diseases.

Bioconjugation: The Fmoc protecting group enables selective reactions, facilitating the conjugation of peptides to various biomolecules, which is essential in creating targeted therapies and diagnostics.

Research in Protein Engineering: Researchers utilize this compound to modify proteins, improving their stability and functionality, which is crucial in fields like biotechnology and synthetic biology.

Analytical Chemistry: It can be employed as a standard in analytical techniques such as HPLC, aiding in the quantification and characterization of peptide samples in various studies.

References

Recent progress in metabolic engineering of Corynebacterium glutamicum for the production of C4, C5, and C6 chemicals

Publication Name: Korean Journal of Chemical Engineering
Publication Date: 2021-06-11
DOI: 10.1007/s11814-021-0788-2

Engineering Corynebacterium glutamicum Mutants for 3-Methyl-1-butanol Production

Publication Name: Biochemical Genetics
Publication Date: 2019-01-14
DOI: 10.1007/s10528-019-09906-4