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Sku CI05134_25_G
Chem Impex
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Product Information

Product Name
Fmoc-pentafluoro-D-phenylalanine
Brand Name
Chem Impex
Product Number
05134
CAS
198545-85-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2775976
IUPAC Name
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(2,3,4,5,6-pentafluorophenyl)propanoic acid
InChI Key
DLOGILOIJKBYKA-QGZVFWFLSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@H(CC4=C(C(=C(C(=C4F)F)F)F)F)C(=O)O

Application

Fmoc-pentafluoro-D-phenylalanine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the stability and reactivity of the resulting peptides.

Drug Development: Its unique fluorinated structure can improve the pharmacokinetic properties of peptide-based drugs, making them more effective in targeting specific biological pathways.

Bioconjugation: The compound is used in bioconjugation techniques, allowing researchers to attach fluorinated amino acids to proteins or other biomolecules, which can aid in imaging and therapeutic applications.

Material Science: In the development of advanced materials, this compound can be incorporated into polymers to enhance their thermal and chemical stability, making them suitable for various industrial applications.

Analytical Chemistry: It can be utilized as a standard in analytical methods, helping to improve the accuracy and reliability of measurements in complex mixtures.