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Sku CI04127_250_MG
Chem Impex
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Product Information

Product Name
Fmoc-3,5-difluoro-L-phenylalanine
Brand Name
Chem Impex
Product Number
04127
CAS
205526-24-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2774201
IUPAC Name
(2S)-3-(3,5-difluorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
InChI Key
UYEQBZISDRNPFC-QFIPXVFZSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@@H(CC4=CC(=CC(=C4)F)F)C(=O)O

Application

Fmoc-3,5-difluoro-L-phenylalanine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its unique fluorinated structure enhances the stability and bioactivity of the resulting peptides.

Drug Development: Researchers leverage its properties to design and develop novel pharmaceuticals, especially in targeting specific receptors due to its ability to modify binding interactions.

Bioconjugation: The compound is used in bioconjugation techniques, allowing for the attachment of biomolecules to peptides, which is crucial in creating targeted drug delivery systems.

Fluorine-Containing Compounds: Its incorporation into various compounds is valuable in medicinal chemistry, as fluorine can enhance metabolic stability and bioavailability of drugs.

Research in Protein Engineering: This chemical aids in the study of protein folding and stability, providing insights into the design of more effective therapeutic proteins.