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Chem Impex
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Product Information

Product Name
4-Chloro-L-phenylalanine
Brand Name
Chem Impex
Product Number
02861
CAS
14173-39-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
736190
IUPAC Name
(2S)-2-amino-3-(4-chlorophenyl)propanoic acid
InChI Key
NIGWMJHCCYYCSF-QMMMGPOBSA-N
SMILES
C1=CC(=CC=C1CC@@H(C(=O)O)N)Cl

Application

4-Chloro-L-phenylalanine is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key building block in synthesizing various pharmaceuticals, particularly those targeting neurological disorders, due to its ability to influence neurotransmitter pathways.

Protein Engineering: Researchers use it to create modified proteins with enhanced properties, allowing for the study of protein interactions and functions, which is crucial in drug discovery and biotechnology.

Biochemical Research: It acts as an important tool in studying the effects of amino acid substitutions on enzyme activity, helping scientists understand metabolic pathways and develop targeted therapies.

Neuroscience Studies: This compound is employed in experiments to investigate the role of specific amino acids in brain function, providing insights into conditions like depression and anxiety.

Food Industry Applications: It can be used in food science research to explore the impact of amino acid profiles on flavor and nutritional value, aiding in the development of healthier food products.

References

Neurochemical Insights into the Role of Tryptophan Metabolites and Kynurenine Pathway in Insomnia and its Psychological and Neurological Comorbidities

Publication Name: Molecular Neurobiology
Publication Date: 2025-07-19
DOI: 10.1007/s12035-025-05210-y

Correction to: Effects of central injection of liver-expressed antimicrobial peptide-2 (LEAP2) on feed intake in broiler chickens: interactions with opioidergic and serotonergic systems

Publication Name: Veterinary Research Communications
Publication Date: 2025-07-10
DOI: 10.1007/s11259-025-10798-6|10.1007/s11259-025-10824-7

Ginsenoside Rg1 alleviates PCPA-induced insomnia by inhibiting NLRP3 inflammasome activation and pyroptosis through the Nrf2/HO-1 pathway in mice

Publication Name: Psychopharmacology
Publication Date: 2025-06-10
DOI: 10.1007/s00213-025-06828-5

Electro-Acupuncture Therapy Alleviates Post-Stroke Insomnia by Regulating Sirt1 and the Nrf2-ARE Pathway

Publication Name: NeuroMolecular Medicine
Publication Date: 2025-05-17
DOI: 10.1007/s12017-025-08862-0