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Chem Impex
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Product Information

Product Name
Fmoc-L-alanine pentafluorophenyl ester
Brand Name
Chem Impex
Product Number
02370
CAS
86060-86-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11059856
IUPAC Name
(2,3,4,5,6-pentafluorophenyl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate
InChI Key
CJXZXBGKOSXBFR-NSHDSACASA-N
SMILES
CC@@H(C(=O)OC1=C(C(=C(C(=C1F)F)F)F)F)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Description

Fmoc-L-alanine pentafluorophenyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures efficiently. Its stability and reactivity make it ideal for solid-phase peptide synthesis.

Drug Development: In pharmaceutical research, it is used to develop new drug candidates, particularly in the design of peptide-based therapeutics. The Fmoc protecting group facilitates selective reactions, enhancing the drug design process.

Bioconjugation: The compound is valuable in bioconjugation techniques, where it helps attach biomolecules to surfaces or other molecules. This application is crucial in developing targeted drug delivery systems.

Analytical Chemistry: It is employed in analytical methods to study protein interactions and modifications, providing insights into biological processes and disease mechanisms.

Material Science: The compound can be used in the development of functional materials, such as hydrogels, that have applications in tissue engineering and regenerative medicine.

References Data Source From Pubchem

Swellographic Study of Peptide Resin Swelling Behavior during Solid Phase Peptide Synthesis

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2007-02-22
DOI: 10.1007/s10989-006-9061-0

Antibody Epitope Mapping Using Arrays of Synthetic Peptides

Publication Name: Antibody Engineering
Publication Date: 2003-12-05
DOI: 10.1385/1-59259-666-5:443

Addition of HOXt (X = A or B) improves the efficiency of phenol-based coupling reagents during peptide synthesis

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2000-03
DOI: 10.1007/bf02443570|10.1023/a:1008967315605

Solvents for Solid-Phase Peptide Synthesis

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 1994
DOI: 10.1385/0-89603-273-6:29