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Product Information

Product Name
N,N'-Disuccinimidyl carbonate
Brand Name
Chem Impex
Product Number
02309
CAS
74124-79-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
676246
IUPAC Name
bis(2,5-dioxopyrrolidin-1-yl) carbonate
InChI Key
PFYXSUNOLOJMDX-UHFFFAOYSA-N
SMILES
C1CC(=O)N(C1=O)OC(=O)ON2C(=O)CCC2=O

Application

N,N'-Disuccinimidyl carbonate is widely utilized in research focused on:

Bioconjugation: This compound serves as a versatile crosslinker for attaching biomolecules, such as proteins and antibodies, to surfaces or other molecules, enhancing the development of targeted therapies and diagnostics.

Vaccine Development: It plays a crucial role in the formulation of vaccines by facilitating the conjugation of antigens to carrier proteins, improving immune response and stability.

Drug Delivery Systems: Researchers use it to create advanced drug delivery systems that allow for controlled release of therapeutics, increasing efficacy while minimizing side effects.

Protein Engineering: The compound is employed in the modification of proteins to study their structure and function, aiding in the design of novel enzymes and therapeutic proteins.

Diagnostics: It is utilized in the development of diagnostic assays, where it helps in the immobilization of biomolecules on solid supports, enhancing sensitivity and specificity in detection methods.

References

An Approach to the Synthesis of Cyclic Photocleavable RNA for Photoactivatable CRISPR/Cas9 System

Publication Name: Russian Journal of Bioorganic Chemistry
Publication Date: 2024-10
DOI: 10.1134/s1068162024050327

Immobilization of Protein Probes on Biochips with Brush Polymer Cells

Publication Name: Russian Journal of Bioorganic Chemistry
Publication Date: 2024-10
DOI: 10.1134/s1068162024050339

Behavioral and Receptor Effects of N-Arachidonoyl-Gaba Under Conditions of Permanent Bilateral Carotid Arteries Stenosis in Rats

Publication Name: Pharmaceutical Chemistry Journal
Publication Date: 2024-09
DOI: 10.1007/s11094-024-03218-7

Rapid immunochemical methods for the analysis of proquinazid in strawberry QuEChERS extracts

Publication Name: Analytical and Bioanalytical Chemistry
Publication Date: 2024-07-09
DOI: 10.1007/s00216-024-05428-0

Irreversible light-activated SpyLigation mediates split-protein assembly in 4D

Publication Name: Nature Protocols
Publication Date: 2024-01-22
DOI: 10.1038/s41596-023-00938-0