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Sku CI00963_5_G
Chem Impex
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Product Information

Product Name
Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide ester
Brand Name
Chem Impex
Product Number
00963
CAS
72040-63-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
83874
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 6-5-(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno3,4-dimidazol-4-ylpentanoylaminohexanoate
InChI Key
UVGHPGOONBRLCX-NJSLBKSFSA-N
SMILES
C1CC(=O)N(C1=O)OC(=O)CCCCCNC(=O)CCCCC@H2C@@H3C@H(CS2)NC(=O)N3

Description

Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide ester is widely utilized in research focused on:

Bioconjugation: This compound is commonly used to attach biotin to proteins or other biomolecules, enhancing their detection and purification in various assays.

Drug Delivery Systems: It plays a crucial role in developing targeted drug delivery systems, where biotinylation allows for specific binding to cells that express biotin receptors, improving therapeutic efficacy.

Diagnostics: The compound is employed in diagnostic applications, such as enzyme-linked immunosorbent assays (ELISA), where biotinylated antibodies can be easily detected and quantified.

Cell Biology: Researchers utilize it in cell culture studies to track and study cellular uptake and localization of biotinylated molecules, providing insights into cellular processes.

Protein Engineering: It is advantageous in protein engineering projects, allowing scientists to modify proteins for enhanced stability and functionality through biotinylation.

References Data Source From Pubchem

The pros and cons of nucleic acid-amplified immunoassays—a comparative study on the quantitation of prostate-specific antigen with and without rolling circle amplification

Publication Name: Analytical and Bioanalytical Chemistry
Publication Date: 2024-06-07
DOI: 10.1007/s00216-024-05357-y

Electrogenerated chemiluminescence from luminol-labelled microbeads triggered by in situ generation of hydrogen peroxide

Publication Name: Analytical and Bioanalytical Chemistry
Publication Date: 2024-06-04
DOI: 10.1007/s00216-024-05356-z

Prussian Blue Nanoparticles in Dot Blot Assay

Publication Name: Science and Global Challenges of the 21st Century – Innovations and Technologies in Interdisciplinary Applications
Publication Date: 2023
DOI: 10.1007/978-3-031-28086-3_39

Molecular mimicry of the receptor-binding domain of the SARS-CoV-2 spike protein: from the interaction of spike-specific antibodies with transferrin and lactoferrin to the antiviral effects of human recombinant lactoferrin

Publication Name: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
Publication Date: 2022-11-05
DOI: 10.1007/s10534-022-00458-6

Pathogen-Associated Molecular Patterns: The Synthesis of Heptose Phosphates and Derivatives

Publication Name: Synthesis
Publication Date: 2021-09-06
DOI: 10.1055/s-0040-1720179