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Product Information

Product Name
N,N'-Diisopropylcarbodiimide
Brand Name
Chem Impex
Product Number
00110
CAS
693-13-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
12734
IUPAC Name
N,N'-di(propan-2-yl)methanediimine
InChI Key
BDNKZNFMNDZQMI-UHFFFAOYSA-N
SMILES
CC(C)N=C=NC(C)C

Description

N,N'-Diisopropylcarbodiimide is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a coupling agent in the formation of peptide bonds, making it essential for synthesizing peptides in pharmaceutical research.

Carboxylic Acid Activation: It effectively activates carboxylic acids for subsequent reactions, streamlining processes in organic synthesis and enhancing yield.

Bioconjugation: Used in bioconjugation techniques, it facilitates the attachment of biomolecules, which is crucial in developing targeted drug delivery systems.

Polymer Chemistry: It plays a significant role in creating polyurethanes and other polymers, contributing to advancements in materials science.

Cross-Linking Agents: This compound is employed as a cross-linking agent in various applications, improving the mechanical properties of materials in industries such as coatings and adhesives.

References Data Source From Pubchem

Facile synthesis of adamantyl and bornyl malonates via catalyst-free transesterification

Publication Name: Journal of Chemical Sciences
Publication Date: 2026-03-02
DOI: 10.1007/s12039-026-02485-z

Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres

Publication Name: Nature Synthesis
Publication Date: 2026-02-11
DOI: 10.1038/s44160-026-00990-0

Uncovering bacterial pseudaminylation with pan-specific antibody tools

Publication Name: Nature Chemical Biology
Publication Date: 2026-02-04
DOI: 10.1038/s41589-025-02114-9

Water-based coupling of amino acids for sustainable solid-phase peptide synthesis

Publication Name: Nature Sustainability
Publication Date: 2026-02-03
DOI: 10.1038/s41893-025-01761-z

Bora bridges Aurora-A activation and substrate recognition of PLK1

Publication Name: EMBO Reports
Publication Date: 2026-01-28
DOI: 10.1038/s44319-025-00687-z