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Sku CI05007_100_G
Chem Impex
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Product Information

Product Name
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
Brand Name
Chem Impex
Product Number
05007
CAS
55750-63-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
5091655
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate
InChI Key
VLARLSIGSPVYHX-UHFFFAOYSA-N
SMILES
C1CC(=O)N(C1=O)OC(=O)CCCCCN2C(=O)C=CC2=O

Description

6-Maleimidohexanoic acid N-hydroxysuccinimide ester is widely utilized in research focused on:

Bioconjugation: This compound is essential for linking biomolecules, such as proteins and antibodies, to various surfaces or labels, enhancing the development of targeted therapies and diagnostics.

Drug Delivery Systems: It plays a crucial role in creating drug delivery vehicles that improve the stability and efficacy of therapeutic agents, particularly in cancer treatment.

Diagnostic Assays: The compound is used in the formulation of assays for detecting specific biomolecules, aiding in disease diagnosis and monitoring.

Protein Engineering: It facilitates the modification of proteins to study their functions and interactions, which is vital for advancing biochemistry and molecular biology.

Surface Functionalization: This chemical is applied in modifying surfaces of materials to enhance their biocompatibility, which is important in medical device manufacturing.

References Data Source From Pubchem

Improvement of tumor-to-blood ratio of radioimmunoconjugates by poly(ethyleneimine)-containing chelating agent

Publication Name: Annals of Nuclear Medicine
Publication Date: 2024-11-25
DOI: 10.1007/s12149-024-02003-6

PD-L1 siRNA hitched polyethyleneimine-elastase constituting nanovesicle induces tumor immunogenicity and PD-L1 silencing for synergistic antitumor immunotherapy

Publication Name: Journal of Nanobiotechnology
Publication Date: 2024-07-27
DOI: 10.1186/s12951-024-02700-4

Hybrid Antimicrobial Coating Based on Conjugate of Hyaluronic Acid with LL-37 Peptide for PEO-Modified Titanium Implants

Publication Name: Russian Journal of Bioorganic Chemistry
Publication Date: 2024-04
DOI: 10.1134/s1068162024020225

A point mutation in GPI-attachment signal peptide accelerates the development of prion disease

Publication Name: Acta Neuropathologica
Publication Date: 2023-03-06
DOI: 10.1007/s00401-023-02553-5

Malaria transmission-blocking conjugate vaccine in ALFQ adjuvant induces durable functional immune responses in rhesus macaques

Publication Name: npj Vaccines
Publication Date: 2021-12-09
DOI: 10.1038/s41541-021-00407-3