Spiroaromatic hydrocarbons are an important class of organic semiconductor building units. Their unique non-planar spiro conjugation effect, cross conformation and steric hindrance effect can effectively improve the optoelectronic properties and device stability of organic semiconductor materials. The one-pot preparation method of spirobifluorene xanthene (SFX) [1,2] has the...
Fluorine-containing molecules have been widely used in modern medicines, pesticides and materials. For example, the selective addition of a fluoroalkyl group to drugs or bioactive molecules often significantly alters their metabolic stability, lipophilicity, and bioactivity. Therefore, there has been considerable interest in developing new and efficient methods...
Fluorine is an important non-metal element. Due to its unique electronegativity, electronic effect and steric hindrance effect, fluorine atoms are often introduced into drugs to regulate drug metabolism pathways, improve metabolic stability and permeability, etc., and have been More than 20% of drugs and pesticides on the...
UiO-66(Zr) is a metal-organic framework material formed from the inorganic metal unit Zr6O4(OH)4 and twelve terephthalic acid ligands. It has two pore cages, tetrahedral and octahedral. Due to the very strong interaction between Zr-O, the UiO-66 (Zr) material has good water stability and thermal stability. The structure...
Chiral sulfoxide compounds are key intermediates in the synthesis of many drugs, such as the proton pump inhibitor esomeprazole, the platelet adhesion inhibitor OPC-29030, the potassium channel activator Aprikalim, etc., and are widely used in drug synthesis. application. At the same time, chiral sulfoxide is also an...
Near-infrared fluorescent dyes are widely used in fluorescence imaging, photothermal and photodynamic therapy, solar photosensitive cells, etc. EC series near-infrared fluorescent dyes are a new type of high-performance dyes developed by the team of Professor Yang Youjun of East China University of Science and Technology. The maximum absorption wavelength is...