Benzyl groups are often used to protect alcohols in multi-step synthetic reactions. To deprotect, the benzyl ether first undergoes oxidative addition to the Pd(0) catalyst, forming a Pd(II) complex. Hydrogen coordination and transfer then facilitates the release of the alcohol. Reductive elimination expels toluene and regenerates the palladium catalyst. Reagents:...

The separation of ionic and ionizable analytes can be effectively achieved using a reversed-phase high performance liquid chromatographic (RP-HPLC) technique called ion-pair chromatography (IPC).  Used on reversed phase columns which are more efficient than columns used in ion exchange chromatography, resulting in better resolution  Sharper peak shapes and highly reproducible results even...

Ion-pair reagents (IPR) are used in reversed-phase liquid chromatography (RP-LC) and has effectively separated ionic or ionizable analytes.  Successful applications of Ion-pair Reagents Single- and double- stranded RNA / biological or synthetic (2011) [1] Stationary Phase: Non-porous polymeric columns and monolithic polymeric capillary columns Ion-Pair Reagent: Various traditional or volatile amine cation salts Detector: Fluorescent-based...

A major challenge in the development of a chromatographic method is the rational selection of experimental conditions that can provide adequate resolution in a reasonable run time. To increase the retention of ionic and polar analytes with a reversed phase column, it is important to choose an oppositely charged ion-pair...

Guide to Safely Transfer Anhydrous Reagents from a Sealed Container for Air Sensitive Reactions Many reactions in the chemistry lab are air or moisture sensitive, often causing potentially catastrophic accidents if mishandled. Common reagents such as lithium aluminum hydride, Grignard reagents, and alkali metals fall under this category. In late...

J&K Scientific is specialized in supplying high quality reagents for viral transport media. We are proud to support the diagnostic efforts in fighting against COVID-19. Reagents for the Preparation of Viral Transport Medium 525484 Phenol red sodium salt [CAS: 34487-61-1] 985371 D-(+)-Glucose, ACS reagent [CAS: 50-99-7] 991468 Potassium chloride, 99%, extra pure [CAS:...