Fluorescent dyes are essential tools for life sciences imaging and molecular tracing, covering a broad spectral range from ultraviolet to near-infrared. Based on their chemical structures, fluorescent dyes can be classified into cyanine dyes (Cy series), rhodamines, fluoresceins, BODIPY dyes, oxazines, and others.
Each class offers distinct performance advantages:
| Dye Class | Key Advantages |
|---|---|
| Cyanine dyes | High molar extinction coefficients, tunable wavelengths – ideal for deep-tissue imaging |
| Rhodamines | Excellent photostability, high fluorescence quantum yields – widely used in confocal microscopy and flow cytometry |
| Fluoresceins | Good water solubility, high biocompatibility – classic choices for immunofluorescence and in situ hybridization |
| BODIPY dyes | Narrow spectra, pH-insensitive – suitable for multicolor imaging and membrane dynamics studies |
In recent years, sulfo-modified dyes have gained widespread adoption for live-cell labeling and protein conjugation due to their significantly enhanced water solubility and reduced non-specific adsorption. Meanwhile, functionalized dyes carrying reactive groups (NHS esters, maleimides, azides, alkynes) have further advanced click chemistry and site-specific biolabeling.
At the application level, fluorescent dyes have become deeply integrated into numerous fields, including:
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Gene sequencing (e.g., multiplex fluorescence capillary electrophoresis)
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qPCR probes
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Immunofluorescence staining
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Live-cell dynamic tracing
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Small animal in vivo imaging
Related Products：
Cyanine Dyes
| Product | CAS | Cat. |
| Cy5, 97% |
195867-59-5 | 9415958 |
| Cy5 SE, 95% |
350686-88-3 | 9415956 |
| Cy5 DIC18, 97% |
75539-51-4 | 9415959 |
| Cy5 DIME, 95% |
48221-03-0 | 9415961 |
| Cy 5, 97% |
146368-15-2 | 971453 |
| Cy5.5, 95% |
1144107-80-1 | 925723 |
| Cy7, 97% |
1144107-78-7 | 984171 |
| Cy7(Me).TEA, 97% |
1251915-04-4 | 954107 |
| Cy7 SE, 95% |
/ | 9436784 |
| Cy7 DIME, 95% |
/ | 9436785 |
| Cy7 NHS Ester, 98% |
477908-53-5 | 985913 |
| Cy3 DIC18, 97% |
22366-93-4 | 9415954 |
| Cy3 DIME, 95% |
25470-94-4 | 9395852 |
| Cy3 SE, 95% |
1032678-38-8 | 965829 |
| Cy3.5-SE, 95% |
871518-83-1 | 9150732 |
| Cy2 DiC18 (3), 95% |
40957-95-7 | 9436783 |
Functional Derivatives of Cyanine Dyes
| Product | CAS | Cat. |
| sulfo Cy3 YNE, 95% |
1010386-62-5 | 2286486 |
| sulfo Cy3.5, 95% |
1284240-77-2 | 2138351 |
| sulfo Cy3-mal.TFA, 95% |
616207-80-8 | 9415994 |
| sulfo Cy3-NH2.TFA, 95% |
/ | 9436779 |
| sulfo Cy3-N3, 95% |
/ | 9436778 |
| sulfo Cy5-YNE, 95% |
1345823-20-2 | 2286481 |
| sulfo Cy5(Et) MAL, 95% |
1160761-43-2 | 9415940 |
| sulfo Cy5(Et)NH2.HCl, 95% |
455253-09-5 | 9416004 |
| sulfo Cy5 NH2, 95% |
2183440-44-8 | 9436787 |
| Sulfo-Cy5(Me)-acid.TEA, 97% |
1121756-16-8 | 2579123 |
| sulfo Cy7.5, 95% |
847180-48-7 | 9416011 |
BODIPY fluorescent dyes
| Product | CAS | Cat. |
| BDP FL N2H3, 95% |
178388-71-1 | 9436791 |
| BDP R6G, 97% |
174881-57-3 | 9423600 |
| BDP558 Acid, 97% |
150173-72-1 | 9423603 |
| BDP558 SE, 95% |
150173-73-2 | 9423602 |
| BDP576-SE, 95% |
201998-61-0 | 9292996 |
| BDP581, 97% |
480999-04-0 | 9415939 |
艳 李
