(Ala1)-PAR-4(1-6)(mouse)

Name: (Ala1)-PAR-4(1-6)(mouse) | 380900-00-5
Brand: US-CATO
SKU: S57CPTD786257_10_MG
Price: 19998.0 USD
Availability: OutOfStock

Cat. No S57CPTD786257_10_MG

Vendor: US-CATO

Product Information

Product Name

(Ala1)-PAR-4(1-6)(mouse)

Brand Name

US-CATO

Product Number

CPTD786257

CAS

380900-00-5

Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

10305353

IUPAC Name

(2S)-2-(2S)-6-amino-2-2-(2S)-1-(2S)-2-(2S)-2-aminopropanoylamino-3-(4-hydroxyphenyl)propanoylpyrrolidine-2-carbonylaminoacetylaminohexanoylamino-3-phenylpropanoic acid

InChI Key

VULJVZXXUQIUEM-OZDPOCAXSA-N

SMILES

CC@@H(C(=O)NC@@H(CC1=CC=C(C=C1)O)C(=O)N2CCCC@H2C(=O)NCC(=O)NC@@H(CCCCN)C(=O)NC@@H(CC3=CC=CC=C3)C(=O)O)N

References

A mouse model of the protease-activated receptor 4 Pro310Leu variant has reduced platelet reactivity

Publication Name: Journal of thrombosis and haemostasis : JTH

Publication Date: 2024-06

DOI: 10.1016/j.jtha.2024.03.004

3,5,2′,4′-Tetramethoxystilbene, a fully methylated resveratrol analog, prevents platelet aggregation and thrombus formation by targeting the protease-activated receptor 4 pathway

Publication Name: Chemico-Biological Interactions

Publication Date: 2022-04-25

DOI: 10.1016/j.cbi.2022.109889

Inhibitory Effects of P2Y12 Receptor Antagonist on PAR1- and PAR4-AP-Induced Platelet Aggregation in Patients with Stroke or TIA

Publication Name: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

Publication Date: 2021-03

DOI: 10.1016/j.jstrokecerebrovasdis.2020.105547

Protease-activated receptor 4 plays a role in lipopolysaccharide-induced inflammatory mechanisms in murine macrophages

Publication Name: Naunyn-Schmiedeberg's Archives of Pharmacology

Publication Date: 2020-11-07

DOI: 10.1007/s00210-020-02014-w

PAK Membrane Translocation and Phosphorylation Regulate Platelet Aggregation Downstream of Gi and G12/13 Pathways

Publication Name: Thrombosis and Haemostasis

Publication Date: 2020-08-27

DOI: 10.1055/s-0040-1714745

(Ala1)-PAR-4(1-6)(mouse)

Product Information

General Information

References

A mouse model of the protease-activated receptor 4 Pro310Leu variant has reduced platelet reactivity

3,5,2′,4′-Tetramethoxystilbene, a fully methylated resveratrol analog, prevents platelet aggregation and thrombus formation by targeting the protease-activated receptor 4 pathway

Inhibitory Effects of P2Y12 Receptor Antagonist on PAR1- and PAR4-AP-Induced Platelet Aggregation in Patients with Stroke or TIA

Protease-activated receptor 4 plays a role in lipopolysaccharide-induced inflammatory mechanisms in murine macrophages

PAK Membrane Translocation and Phosphorylation Regulate Platelet Aggregation Downstream of Gi and G12/13 Pathways