Z-Leu-Tyr-chloromethylketone

Name: Z-Leu-Tyr-chloromethylketone | 56979-35-2
Brand: US-CATO
SKU: S57CPTD785576_100_MG
Price: 19998.0 USD
Availability: OutOfStock

Cat. No S57CPTD785576_100_MG

Vendor: US-CATO

Product Information

Product Name

Z-Leu-Tyr-chloromethylketone

Brand Name

US-CATO

Product Number

CPTD785576

CAS

56979-35-2

Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

171556

IUPAC Name

benzyl N-(2S)-1-(2S)-4-chloro-1-(4-hydroxyphenyl)-3-oxobutan-2-ylamino-4-methyl-1-oxopentan-2-ylcarbamate

InChI Key

BXNJBFCUDNXPPQ-SFTDATJTSA-N

SMILES

CC(C)CC@@H(C(=O)NC@@H(CC1=CC=C(C=C1)O)C(=O)CCl)NC(=O)OCC2=CC=CC=C2

References

Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers in Vitro and in Vivo

Publication Name: Journal of Medicinal Chemistry

Publication Date: 2020-02-07

DOI: 10.1021/acs.jmedchem.9b01746

Mechanisms of AVP‐induced glucagon release in clonal α‐cells In‐R1‐G9: involvement of Ca2+‐dependent and ‐independent pathways

Publication Name: British Journal of Pharmacology

Publication Date: 2000-01

DOI: 10.1038/sj.bjp.0703037

Activation of phospholipase D is an early event in integrin-mediated signalling leading to phagocytosis in human neutrophils

Publication Name: Inflammation

Publication Date: 1996-08

DOI: 10.1007/bf01486745

The chymotrypsin inhibitor carbobenzyloxy-leucine-tyrosine-chloromethylketone interferes with the neutrophil respiratory burst mediated by a signaling pathway independent of PtdInsP2 breakdown and cytosolic free calcium

Publication Name: Journal of immunology (Baltimore, Md. : 1950)

Publication Date: 1991-09-15

DOI: 10.4049/jimmunol.147.6.1912

The chymotrypsin inhibitor carbobenzyloxy-leucine-tyrosine-chloromethylketone interferes with phospholipase D activation induced by formyl-methionyl-leucyl-phenylalanine in human neutrophils

Publication Name: The Journal of biological chemistry

Publication Date: 1991-08-25

DOI: 10.1016/s0021-9258(18)98489-9

Z-Leu-Tyr-chloromethylketone

Product Information

General Information

References

Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers in Vitro and in Vivo

Mechanisms of AVP‐induced glucagon release in clonal α‐cells In‐R1‐G9: involvement of Ca2+‐dependent and ‐independent pathways

Activation of phospholipase D is an early event in integrin-mediated signalling leading to phagocytosis in human neutrophils

The chymotrypsin inhibitor carbobenzyloxy-leucine-tyrosine-chloromethylketone interferes with the neutrophil respiratory burst mediated by a signaling pathway independent of PtdInsP2 breakdown and cytosolic free calcium

The chymotrypsin inhibitor carbobenzyloxy-leucine-tyrosine-chloromethylketone interferes with phospholipase D activation induced by formyl-methionyl-leucyl-phenylalanine in human neutrophils