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Sku CI37445_1_ML
Chem Impex
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Product Information

Product Name
2'-Deoxyadenosine-5'-triphosphate sodium salt solution, 100 mM solution, pH 7
Brand Name
Chem Impex
Product Number
37445
CAS
1927-31-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
15993
IUPAC Name
(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-ylmethoxy-hydroxyphosphoryl phosphono hydrogen phosphate
InChI Key
SUYVUBYJARFZHO-RRKCRQDMSA-N
SMILES
C1C@@H(C@H(OC@H1N2C=NC3=C(N=CN=C32)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O

Application

2'-Deoxyadenosine-5'-triphosphate sodium salt solution, 100 mM solution, pH 7 is widely utilized in research focused on:

Biochemical Research: This compound serves as a crucial substrate in various enzymatic reactions, particularly in studies involving DNA synthesis and repair mechanisms.

Molecular Biology: It is commonly used in polymerase chain reaction (PCR) protocols, aiding in the amplification of DNA, which is essential for genetic analysis and cloning.

Cell Culture: The solution is employed in cell culture media to support the growth and maintenance of cells, providing necessary energy and substrates for cellular processes.

Pharmaceutical Development: Researchers utilize this compound in drug formulation studies, particularly in the development of nucleoside analogs that can inhibit viral replication.

Diagnostics: It plays a role in diagnostic assays, such as those used in detecting genetic disorders or pathogens, by facilitating the synthesis of specific nucleic acid sequences.

References

DNA polymerization activates RNA cleavage of a reverse transcriptase–like antiviral enzyme

Publication Name: Science (New York, N.Y.)
Publication Date: 2026-05-21
DOI: 10.1126/science.aef3178

Pol γ possesses separate metal binding sites for polymerase and strand displacement functions

Publication Name: bioRxiv : the preprint server for biology
Publication Date: 2026-01-25
DOI: 10.64898/2026.01.25.701366

Risk Assessment and International Biosafety Guidelines for the Enzyme Replacement Therapy in the Pharmaceutical Sector

Publication Name: Pharmaceutically Relevant Microbial Enzymes
Publication Date: 2026
DOI: 10.1007/978-981-95-4941-2_2

How ATP and dATP reposition class III ribonucleotide reductase cone domains to regulate enzyme activity

Publication Name: Science Advances
Publication Date: 2025-11-28
DOI: 10.1126/sciadv.ady9156