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Sku CI30040_5_G
Chem Impex
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Product Information

Product Name
2-Chloroadenosine
Brand Name
Chem Impex
Product Number
30040
CAS
146-77-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
8974
IUPAC Name
(2R,3R,4S,5R)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChI Key
BIXYYZIIJIXVFW-UUOKFMHZSA-N
SMILES
C1=NC2=C(N=C(N=C2N1C@H3C@@H(C@@H(C@H(O3)CO)O)O)Cl)N

Application

2-Chloroadenosine is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key building block in the synthesis of various antiviral and anticancer agents, providing researchers with a pathway to develop targeted therapies.

Cell Signaling Studies: It is used to investigate adenosine receptors in cellular signaling pathways, helping scientists understand their roles in processes like inflammation and immune response.

Neuroscience Research: The compound is instrumental in studying neuroprotective effects, particularly in models of neurodegenerative diseases, offering insights into potential treatments.

Biochemical Assays: 2-Chloroadenosine is employed in assays to measure enzyme activity related to nucleotide metabolism, aiding in the development of diagnostic tools.

Drug Interaction Studies: It helps researchers explore interactions between drugs and adenosine receptors, which is crucial for optimizing therapeutic regimens and minimizing side effects.

References

Astrocytes Control Norepinephrine Signaling in the Brain

Publication Name: Neuroscience Bulletin
Publication Date: 2025-11-20
DOI: 10.1007/s12264-025-01551-9

Deficiency of KMT2D causes autistic-like behavior in mice and zebrafish

Publication Name: Communications Biology
Publication Date: 2025-08-29
DOI: 10.1038/s42003-025-08635-2

Purinergic receptors in atherosclerosis: implications for pathophysiology and therapeutic strategies

Publication Name: Journal of Physiology and Biochemistry
Publication Date: 2025-07-16
DOI: 10.1007/s13105-025-01108-4