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Product Information

Product Name
Fmoc-L-valine
Brand Name
Chem Impex
Product Number
02470
CAS
68858-20-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
688217
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoic acid
InChI Key
UGNIYGNGCNXHTR-SFHVURJKSA-N
SMILES
CC(C)C@@H(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Application

Fmoc-L-valine is widely utilized in research focused on

Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without affecting other functional groups.

Drug Development: Researchers use Fmoc-L-valine in the design of peptide-based therapeutics, enhancing the stability and bioavailability of drug candidates.

Biotechnology: In the production of recombinant proteins, this chemical aids in the incorporation of specific amino acids, improving the yield and functionality of the proteins.

Analytical Chemistry: Fmoc-L-valine is employed in chromatography techniques for the separation and analysis of amino acids and peptides, providing high-resolution results.

Education and Training: This compound is commonly used in academic laboratories to teach students about peptide synthesis and the importance of protecting groups in organic chemistry.

References

A short-lived peptide signal regulates cell-to-cell communication in Listeria monocytogenes

Publication Name: Communications Biology
Publication Date: 2024-08-03
DOI: 10.1038/s42003-024-06623-6

Design, synthesis and bioactivity evaluation of novel monomethyl auristatin F analogues

Publication Name: Molecular Diversity
Publication Date: 2024-05-18
DOI: 10.1007/s11030-024-10873-1

Antimicrobial activity and properties of de novo design of short synthetic lipopeptides

Publication Name: Folia Microbiologica
Publication Date: 2024-01-26
DOI: 10.1007/s12223-024-01132-9

Preparation of Mucin Glycopeptides by Organic Synthesis

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2024
DOI: 10.1007/978-1-0716-3670-1_16

Improved LC–MS identification of short homologous peptides using sequence-specific retention time predictors

Publication Name: Analytical and Bioanalytical Chemistry
Publication Date: 2023-03-31
DOI: 10.1007/s00216-023-04670-2