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Chem Impex
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Product Information

Product Name
Na-Fmoc-Nw-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
Brand Name
Chem Impex
Product Number
01964
CAS
154445-77-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11354259
IUPAC Name
(2S)-5-amino-(2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl)sulfonylaminomethylideneamino-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid
InChI Key
HNICLNKVURBTKV-NDEPHWFRSA-N
SMILES
CC1=C(C(=C(C2=C1OC(C2)(C)C)C)S(=O)(=O)NC(=NCCCC@@H(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)N)C

Application

Na-Fmoc-Nw-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protective group in peptide synthesis, allowing for the selective modification of amino acids. Its stability under various conditions makes it ideal for complex peptide sequences.

Drug Development: In pharmaceutical research, it aids in the design of peptide-based drugs, particularly those targeting specific receptors. Its unique structure enhances binding affinity and specificity.

Bioconjugation: The sulfonyl group allows for efficient conjugation with biomolecules, facilitating the development of targeted delivery systems in therapeutics, particularly in cancer treatment.

Research in Neuroscience: This compound can be used in studies related to neuropeptides, helping researchers understand signaling pathways and potential therapeutic targets for neurological disorders.

Analytical Chemistry: It is useful in the development of analytical methods for detecting and quantifying peptides in biological samples, providing insights into metabolic processes and disease states.

References Data Source From Pubchem

Potential Enhancement of Topical Drug Delivery Using Grapefruit-derived Nanoparticles Modified Using TAT Peptide

Publication Name: Pharmaceutical Research
Publication Date: 2026-01-21
DOI: 10.1007/s11095-026-04014-6

Identification of an αvβ3-targeting bicyclic peptide with atypical norArg-Gly-Asp sequence

Publication Name: Communications Chemistry
Publication Date: 2026-01-12
DOI: 10.1038/s42004-026-01886-y

Mirror-Image Human Serum Albumin Domain III as a Tool for Analyzing Site II-Dependent Molecular Recognition

Publication Name: Synthesis of Functional Characterization of Protein Domains for the Development of Mirror-Image Therapeutics
Publication Date: 2026
DOI: 10.1007/978-981-95-5366-2_3

Synthetic Studies on the Extracellular Domain of the T Cell Immunoreceptor with Immunoglobulin and Immunoreceptor Tyrosine-Based Inhibitory Motif Domain (TIGIT) Using Trt-K10 Solubilizing Tags

Publication Name: Synthesis of Functional Characterization of Protein Domains for the Development of Mirror-Image Therapeutics
Publication Date: 2026
DOI: 10.1007/978-981-95-5366-2_2