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Sku CI00876_100_MG
Chem Impex
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Product Information

Product Name
2',3'-Dideoxyinosine
Brand Name
Chem Impex
Product Number
00876
CAS
69655-05-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
135398739
IUPAC Name
9-(2R,5S)-5-(hydroxymethyl)oxolan-2-yl-1H-purin-6-one
InChI Key
BXZVVICBKDXVGW-NKWVEPMBSA-N
SMILES
C1CC@@H(OC@@H1CO)N2C=NC3=C2N=CNC3=O

Application

2',3'-Dideoxyinosine is widely utilized in research focused on

Antiviral Treatments: This compound is primarily used in the development of antiviral medications, particularly for treating HIV. Its ability to inhibit viral replication makes it a crucial component in combination therapies.

Research in Nucleoside Analogues: It serves as a model compound in studies aimed at understanding nucleoside analogues, which can lead to the development of new drugs with improved efficacy and reduced side effects.

Cellular Mechanism Studies: Researchers utilize it to investigate cellular mechanisms of drug resistance in viral infections, providing insights that can inform future therapeutic strategies.

Pharmaceutical Formulations: In the pharmaceutical industry, it is used in the formulation of oral medications, benefiting from its favorable pharmacokinetic properties that enhance drug delivery.

Combination Therapy Research: It plays a key role in studies exploring combination therapies, helping to identify synergistic effects with other antiviral agents, which can lead to more effective treatment regimens.

References

Early pandemic HIV-1 integration site preferences differ across anatomical sites

Publication Name: Communications Medicine
Publication Date: 2025-10-06
DOI: 10.1038/s43856-025-01146-5

Drug-Induced Retinal Toxicity

Publication Name: Advances in experimental medicine and biology
Publication Date: 2025
DOI: 10.1007/978-3-031-72230-1_50

PREVALENCE OF DIDANOSINE-RELATED RETINAL TOXICITY AT AN URBAN ACADEMIC CENTER AS DIAGNOSED WITH ULTRA-WIDEFIELD IMAGING

Publication Name: Retina (Philadelphia, Pa.)
Publication Date: 2024-10-01
DOI: 10.1097/iae.0000000000004175

2′-β-Methylselenyl nucleos(t)ide analogs as reverse transcriptase inhibitors against diverse HIV mutants

Publication Name: Bioorganic & Medicinal Chemistry
Publication Date: 2024-08-01
DOI: 10.1016/j.bmc.2024.117813