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Product Information

Product Name
Boc-N-methyl-L-valine
Brand Name
Chem Impex
Product Number
02679
CAS
45170-31-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7010608
IUPAC Name
(2S)-3-methyl-2-methyl-(2-methylpropan-2-yl)oxycarbonylaminobutanoic acid
InChI Key
XPUAXAVJMJDPDH-QMMMGPOBSA-N
SMILES
CC(C)C@@H(C(=O)O)N(C)C(=O)OC(C)(C)C

Application

Boc-N-methyl-L-valine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals and biologics. Its protective Boc group allows for selective reactions, enhancing the efficiency of peptide assembly.

Drug Development: Researchers leverage Boc-N-methyl-L-valine in the design of novel drug candidates, especially in the field of oncology and immunology, where modified peptides can improve therapeutic efficacy and reduce side effects.

Protein Engineering: This chemical is used in the modification of proteins to study structure-function relationships, aiding in the development of more effective enzymes and therapeutic proteins.

Biotechnology: In biotechnological applications, Boc-N-methyl-L-valine is employed in the production of peptide-based vaccines, which can stimulate specific immune responses against pathogens.

Research in Neuroscience: The compound is also explored in neuroscience for its potential role in developing neuroprotective agents, contributing to the advancement of treatments for neurodegenerative diseases.

References Data Source From Pubchem

Design, synthesis and bioactivity evaluation of novel monomethyl auristatin F analogues

Publication Name: Molecular Diversity
Publication Date: 2024-05-18
DOI: 10.1007/s11030-024-10873-1

Synthesis of Majusculamides A and B

Publication Name: Synlett
Publication Date: 2019-04-12
DOI: 10.1055/s-0037-1611805

Design, synthesis, and in vitro antiplasmodial activity of 4-aminoquinolines containing modified amino acid conjugates

Publication Name: Medicinal Chemistry Research
Publication Date: 2016-03-25
DOI: 10.1007/s00044-016-1555-5

Asymmetric Transfer Hydrogenation of Ketimines with Trichlorosilane: Structural Studies

Publication Name: Synthesis
Publication Date: 2009-04-14
DOI: 10.1055/s-0028-1088045