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Sku CI07110_5_G
Chem Impex
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Product Information

Product Name
Fmoc-O-trityl-D-threonine
Brand Name
Chem Impex
Product Number
07110
CAS
682800-84-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
51340541
IUPAC Name
(2R,3S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-trityloxybutanoic acid
InChI Key
JARBLLDDSTVWSM-OSPAZUARSA-N
SMILES
CC@@H(C@H(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)OC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6

Application

Fmoc-O-trityl-D-threonine is widely utilized in research focused on

Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups. This is particularly useful in the pharmaceutical industry for developing new drugs.

Bioconjugation: It is employed in bioconjugation techniques to attach biomolecules, such as proteins or nucleic acids, to surfaces or other molecules. This application is vital in the development of targeted therapies and diagnostics.

Research in Protein Engineering: Researchers use this compound to study protein folding and stability, which can lead to advancements in enzyme design and therapeutic proteins, enhancing drug efficacy.

Development of Antibody-Drug Conjugates: Fmoc-O-trityl-D-threonine is instrumental in creating antibody-drug conjugates, which are designed to deliver cytotoxic drugs directly to cancer cells, minimizing damage to healthy tissue.

Custom Synthesis Services: Companies specializing in custom peptide synthesis utilize this compound to provide tailored solutions for clients in academia and industry, ensuring high-quality and specific peptide sequences for research and therapeutic purposes.