Cat. No S57C1830160_5_MG
US-CATO

Product Information

Product Name
Orforglipron
Brand Name
US-CATO
Product Number
C1830160
CAS
2212020-52-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
137319706
IUPAC Name
3-(1S,2S)-1-5-(4S)-2,2-dimethyloxan-4-yl-2-(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-3-(4-fluoro-1-methylindazol-5-yl)-2-oxoimidazol-1-yl-4-methyl-6,7-dihydro-4H-pyrazolo4,3-cpyridine-5-carbonylindol-1-yl-2-methylcyclopropyl-4H-1,2,4-oxadiazol-5-one
InChI Key
USUWIEBBBWHKNI-KHIFEHGGSA-N
SMILES
CC@H1CC@1(C2=NOC(=O)N2)N3C4=C(C=C(C=C4)C@H5CCOC(C5)(C)C)C=C3C(=O)N6CCC7=NN(C(=C7C@@H6C)N8C=CN(C8=O)C9=C(C1=C(C=C9)N(N=C1)C)F)C1=CC(=C(C(=C1)C)F)C

References Data Source From Pubchem

Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes

Publication Name: The New England journal of medicine
Publication Date: 2025-09-18
DOI: 10.1056/nejmoa2505669

The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipron

Publication Name: Science Translational Medicine
Publication Date: 2024-12-18
DOI: 10.1126/scitranslmed.adp5765

Effects of once-daily oral orforglipron on weight and metabolic markers: a systematic review and meta-analysis of randomized controlled trials

Publication Name: Archives of Endocrinology and Metabolism
Publication Date: 2024-09-11
DOI: 10.20945/2359-4292-2023-0469

Binding sites and design strategies for small molecule GLP-1R agonists

Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2024-09-05
DOI: 10.1016/j.ejmech.2024.116632

Orforglipron

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