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Sku SC07-1411_50_MG
US-Strem
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Product Information

Product Name
(4R,4'R,5S,5'S)-2,2'-Cyclopropylidenebis4,5-dihydro-4,5-diphenyloxazole, 98%, (99% ee)
Brand Name
US-Strem
Product Number
07-1411
CAS
229184-96-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
12080386
IUPAC Name
(4R,5S)-2-1-(4R,5S)-4,5-diphenyl-4,5-dihydro-1,3-oxazol-2-ylcyclopropyl-4,5-diphenyl-4,5-dihydro-1,3-oxazole
InChI Key
UAXGHJCFHMQPBJ-XAZDILKDSA-N
SMILES
C1CC1(C2=NC@@H(C@@H(O2)C3=CC=CC=C3)C4=CC=CC=C4)C5=NC@@H(C@@H(O5)C6=CC=CC=C6)C7=CC=CC=C7

Safety Information

Storage Condition
Store at 2-8℃

Application

Technical Notes:
1.Ligand used in the Ru- and Cu-catalyzed enantios elective propargylic alkylation of propargylic alcohols with ß-ketoesters 1 and ß-keto phosphonates.
2.Used in the synthesis of highly substituted chiral v-lactams via catalytic asymmetric formal 3+2
cycloaddition of 2-isocyanatomalonate esters and uns aturated imines .
3.Ligand for the Cu-catalyzed 3+2- and 3+3-cycloadditions of(Z)-v-ethyI enoldiazoacetate with diaziridine.

References Data Source From Pubchem

Enantioselective Synthesis of γ-Lactams by [3+2] Cycloaddition

Publication Name: Synfacts
Publication Date: 2017-12-15
DOI: 10.1055/s-0036-1591073

Recent Advances in the Catalytic Asymmetric Construction of Phosphorus-Substituted Quaternary Carbon Stereocenters

Publication Name: Synthesis
Publication Date: 2017-11-27
DOI: 10.1055/s-0036-1590958

Stereoselective SN1-Type Reaction of Enols and Enolates

Publication Name: Synthesis
Publication Date: 2017-06-13
DOI: 10.1055/s-0036-1588871

Nickel-Catalyzed Enantioselective Friedel–Crafts Alkylation of Indoles with β,β-Disubstituted Nitroalkenes

Publication Name: Synlett
Publication Date: 2015-11-23
DOI: 10.1055/s-0035-1560538