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Sku CI35143_25_MG
Chem Impex
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Product Information

Product Name
L-Homopropargylglycine hydrochloride
Brand Name
Chem Impex
Product Number
35143
CAS
98891-36-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11344028
IUPAC Name
(2S)-2-aminohex-5-ynoic acid
InChI Key
SCGJGNWMYSYORS-YFKPBYRVSA-N
SMILES
C#CCCC@@H(C(=O)O)N

Application

L-Homopropargylglycine hydrochloride is widely utilized in research focused on various applications:

Biochemical Research: This compound serves as a potent inhibitor of cystathionine γ-lyase, making it valuable for studying sulfur amino acid metabolism and its implications in diseases such as cancer.

Neuroscience: Researchers use it to explore its neuroprotective effects, particularly in models of neurodegenerative diseases, helping to understand mechanisms of neuronal survival.

Pharmaceutical Development: Its unique structure allows for the design of novel drugs targeting metabolic pathways, offering potential advantages over traditional compounds in specificity and efficacy.

Plant Biology: In agricultural studies, it aids in understanding plant responses to stress, contributing to the development of crops that can better withstand environmental challenges.

Analytical Chemistry: The compound is employed in various assays to measure enzyme activity, providing insights into metabolic disorders and potential therapeutic targets.

References Data Source From Pubchem

SLC6A6 imports taurine into mitochondria to sustain mitochondrial translation and tumour growth

Publication Name: Nature Metabolism
Publication Date: 2026-02-06
DOI: 10.1038/s42255-026-01455-6

Monovalent pseudo-natural products supercharge degradation of IDO1 by its native E3 KLHDC3

Publication Name: Nature Chemistry
Publication Date: 2026-01-07
DOI: 10.1038/s41557-025-02021-5

Functional Divergence of bL36m Protein in Yeast and Human Mitochondrial Ribosomes

Publication Name: Biochemistry. Biokhimiia
Publication Date: 2026-01
DOI: 10.1134/s000629792560348x

The cancer-testis lncRNA LINC01940 promotes gastric cancer malignant progression and chemoresistance by enhancing ribosome biogenesis via TAF15-mediated NOL11 SUMOylation

Publication Name: Cellular & Molecular Biology Letters
Publication Date: 2025-12-16
DOI: 10.1186/s11658-025-00840-5

Evolutionary characterization of antiviral SAMD9/9L across kingdoms supports ancient convergence and lineage-specific adaptations

Publication Name: Nature Ecology & Evolution
Publication Date: 2025-11-11
DOI: 10.1038/s41559-025-02845-x