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Sku CI29674_100_MG
Chem Impex
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Product Information

Product Name
Fmoc-N-(propargyl)-glycine
Brand Name
Chem Impex
Product Number
29674
CAS
1033622-38-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
24820584
IUPAC Name
2-9H-fluoren-9-ylmethoxycarbonyl(prop-2-ynyl)aminoacetic acid
InChI Key
BTHZEMFPZILBCR-UHFFFAOYSA-N
SMILES
C#CCN(CC(=O)O)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Application

Fmoc-N-(propargyl)-glycine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for drug development and biological studies.

Bioconjugation: Its unique propargyl group enables efficient bioconjugation reactions, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in drug delivery systems.

Fluorescent Labeling: The Fmoc protecting group can be easily removed under mild conditions, making it ideal for incorporating fluorescent tags into peptides, enhancing visualization in cellular studies.

Research in Neuroscience: This compound is used in the development of neuropeptides, which can help in understanding neurological pathways and potential treatments for neurodegenerative diseases.

Custom Drug Design: Its versatility allows for modifications that can lead to the creation of novel therapeutic agents, addressing specific medical needs and improving efficacy compared to traditional compounds.

References Data Source From Pubchem

CuAAC ‘Click’ in Carbohydrate Chemistry

Publication Name: Materials Horizons: From Nature to Nanomaterials
Publication Date: 2024
DOI: 10.1007/978-981-97-4596-8_13

On-Resin Click-Glycoconjugation of Peptoids

Publication Name: Synthesis
Publication Date: 2009-01-09
DOI: 10.1055/s-0028-1083302