$2,151.50

FREE
SHIPPING

100% MONEY
BACK GUARANTEE

ONLINE
SUPPORT 24/7

Available on backorder. No lead time available. Please request a quote.
Sku CI05998_25_G
Chem Impex
Get Bulk Quote

Product Information

Product Name
D-Propargylglycine
Brand Name
Chem Impex
Product Number
05998
CAS
23235-03-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6992713
IUPAC Name
(2R)-2-aminopent-4-ynoic acid
InChI Key
DGYHPLMPMRKMPD-SCSAIBSYSA-N
SMILES
C#CCC@H(C(=O)O)N

Application

D-Propargylglycine is widely utilized in research focused on:

Neuropharmacology: This compound acts as an inhibitor of the enzyme cystathionine γ-lyase, which is involved in the production of hydrogen sulfide, a signaling molecule in the brain. Its application helps in studying neurodegenerative diseases and potential therapies.

Metabolic Studies: Researchers use D-Propargylglycine to investigate metabolic pathways involving sulfur-containing amino acids. This aids in understanding metabolic disorders and developing nutritional interventions.

Cardiovascular Research: The compound's role in modulating hydrogen sulfide levels makes it valuable for studying cardiovascular health, particularly in conditions like hypertension and heart failure.

Pharmaceutical Development: D-Propargylglycine serves as a lead compound in the synthesis of new drugs targeting various diseases, providing a scaffold for the development of novel therapeutic agents.

Biochemical Assays: It is commonly used in laboratory assays to measure enzyme activity related to sulfur metabolism, offering insights into various biochemical processes and disease mechanisms.

References Data Source From Pubchem

Chiral lipid bilayers are enantioselectively permeable

Publication Name: Nature Chemistry
Publication Date: 2021-06-10
DOI: 10.1038/s41557-021-00708-z

Preparation Using Aminopeptidase from P. putida ATCC 12633

Publication Name: Science of Synthesis
Publication Date: 2015

Palladium-Catalyzed Cyclization of α-Propargyl α-Amino Esters

Publication Name: Science of Synthesis
Publication Date: 2007

Chloroalanyl and propargylglycyl dipeptides. Suicide-substrate-containing antibacterials

Publication Name: Journal of Medicinal Chemistry
Publication Date: 1983-12
DOI: 10.1021/jm00366a015