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Sku CI02726_25_G
Chem Impex
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Product Information

Product Name
L-Propargylglycine
Brand Name
Chem Impex
Product Number
02726
CAS
23235-01-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
168091
IUPAC Name
(2S)-2-aminopent-4-ynoic acid
InChI Key
DGYHPLMPMRKMPD-BYPYZUCNSA-N
SMILES
C#CCC@@H(C(=O)O)N

Application

L-Propargylglycine is widely utilized in research focused on:

Biochemical Research: It serves as a potent inhibitor of the enzyme cystathionine gamma-lyase, which is crucial in studying sulfur metabolism and its implications in various diseases.

Neuroscience: Researchers use it to investigate the role of hydrogen sulfide in neuroprotection and neurodegenerative diseases, providing insights into potential therapeutic strategies.

Pharmaceutical Development: This compound is explored for its potential use in developing drugs targeting metabolic disorders, particularly those linked to cysteine and homocysteine metabolism.

Agricultural Science: It is being studied for its effects on plant growth and stress responses, offering potential applications in enhancing crop resilience.

Analytical Chemistry: L-Propargylglycine is utilized as a standard in various analytical methods, aiding in the accurate measurement of related compounds in biological samples.

References Data Source From Pubchem

d-cysteine impairs tumour growth by inhibiting cysteine desulfurase NFS1

Publication Name: Nature Metabolism
Publication Date: 2025-08-12
DOI: 10.1038/s42255-025-01339-1

Accessing elusive σ-type cyclopropenium cation equivalents through redox gold catalysis

Publication Name: Nature Chemistry
Publication Date: 2024-05-23
DOI: 10.1038/s41557-024-01535-8

The alkynyl-containing compounds from mushrooms and their biological activities

Publication Name: Natural Products and Bioprospecting
Publication Date: 2023-01-03
DOI: 10.1007/s13659-022-00368-7|10.1007/s13659-023-00416-w

Intermolecular CuAAC Click Conjugation of Carbohydrates

Publication Name: Science of Synthesis
Publication Date: 2021